Zhang Tian-Jiao, Shen Zhen, Li Min, Zhu Jing, Li Yue-Bo, Wei Wei, Zhou Hang-Cheng, Zhao Wei-Dong, Wu Da-Bao, Zhou Ying
Department of Obstetrics and Gynaecology, The First Affiliated Hospital of University of Science & Technology of China, Anhui Provincial Hospital, Hefei, Anhui Province, China.
Department of Radiology, The First Affiliated Hospital of University of Science & Technology of China, Anhui Provincial Hospital, Hefei, Anhui Province, China.
J Int Med Res. 2021 Feb;49(2):300060520987725. doi: 10.1177/0300060520987725.
Choriocarcinoma is a highly malignant gynaecological tumour. This disease becomes life-threatening once brain haemorrhage or brain herniation occurs. Timely and accurate brain surgery can gain treatment time for patients that have a large number of cerebral haemorrhages and/or brain herniation. This current report describes a case of choriocarcinoma secondary to a hydatidiform mole in a 55-year-old woman that presented with neurological symptoms. Following admission to hospital, computed tomography examination found that lung and brain metastases were accompanied by cerebral haemorrhage. Cerebral hernia occurred during induction chemotherapy treatment and emergency surgery was performed. The patient recovered after individual chemotherapy and rehabilitation treatment. Patients with a very high risk of choriocarcinoma with brain metastasis should be referred to a comprehensive medical centre. Necessary surgical treatment and individualized chemotherapy can reduce the mortality of patients with choriocarcinoma brain metastasis.
绒毛膜癌是一种高度恶性的妇科肿瘤。一旦发生脑出血或脑疝,这种疾病就会危及生命。对于有大量脑出血和/或脑疝的患者,及时、准确的脑部手术可以为其赢得治疗时间。本报告描述了一例55岁女性葡萄胎继发绒毛膜癌并出现神经症状的病例。入院后,计算机断层扫描检查发现肺部和脑部转移并伴有脑出血。诱导化疗期间发生脑疝,遂进行了急诊手术。患者经过个体化化疗和康复治疗后康复。绒毛膜癌脑转移风险极高的患者应转诊至综合医疗中心。必要的手术治疗和个体化化疗可以降低绒毛膜癌脑转移患者的死亡率。