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“U”型入路经皮椎间孔镜腰椎间盘切除术治疗腰椎管狭窄症合并椎间盘突出症慢性腰痛患者的临床疗效

Clinical Outcomes of "U" Route Transforaminal Percutaneous Endoscopic Lumbar Discectomy in Chronic Pain Patients with Lumbar Spinal Stenosis Combined with Disc Herniation.

机构信息

Department of Pain Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Department of Orthopedics, The Affiliated Suqian Hospital of Xuzhou Medical University, Suqian, China.

出版信息

Pain Res Manag. 2021 Jan 19;2021:6657463. doi: 10.1155/2021/6657463. eCollection 2021.

Abstract

INTRODUCTION

"U" route transforaminal percutaneous endoscopic lumbar discectomy (PELD) was introduced for lumbar spinal stenosis (LSS) combined with disc herniation (DH) treatment. This study aims to explore the efficacy and safety of "U" route PELD on chronic pain patients with LSS combined with DH.

METHODS

Degenerative LSS combined with DH patients who underwent "U" route PELD were reexamined, and 80 patients were recruited and followed up for 2 years. The other 80 healthy individuals who were age- and sex-matched to the patients without chronic pain were enrolled as healthy controls. Minimum dura sac cross-sectional area (mDCSA) by MRI, Visual Analog Scale (VAS), Oswestry Disability Index (ODI), and modified MacNab outcomes were assessed. Emotional evaluation of pain catastrophizing and depression was documented with Pain Catastrophizing Scale (PCS) and Beck Depression Inventory (BDI), respectively, for patients before and after surgery and healthy individuals.

RESULTS

All patients were of the age range from 47 to 85 years, with an average of 59.5 ± 9.76 years. Symptoms duration was 114.6 ± 22.77 months, operation time was 87.7 ± 25.20 minutes, and the average hospital stay was 5.8 ± 2.81 days. Four patients quit, and hence, a total of 76 patients completed the follow-up. The results indicated that mDCSA was improved significantly after operation ( < 0.001), either low back and leg VAS or ODI decreased over time ( < 0.001), and the excellent-to-good rate was improved from 88.75% to 93.42% during postoperative 2 years ( < 0.05). Complications of dural tear, nerve root, or dysesthesia were reported in 5 patients, and all recovered after conservative therapy. The scores of pain catastrophizing were reduced after operation ( < 0.001), but no significance of BDI was found between patients and healthy controls ( > 0.05).

CONCLUSIONS

The "U" route PELD seems an alternative to LSS combined with DH treatment, which might reach a better decompression and effectively improve chronic pain conditions. Still, the complications were potential and required further consideration.

摘要

引言

“U”形经皮椎间孔内窥镜腰椎间盘切除术(PELD)被引入用于治疗腰椎管狭窄症(LSS)合并椎间盘突出症(DH)。本研究旨在探讨“U”形 PELD 治疗 LSS 合并 DH 慢性疼痛患者的疗效和安全性。

方法

对接受“U”形 PELD 的退行性 LSS 合并 DH 患者进行复查,共纳入 80 例患者并随访 2 年。同时招募了 80 名年龄和性别与患者相匹配、无慢性疼痛的健康个体作为健康对照组。通过 MRI 评估最小硬脑膜囊横截面积(mDCSA)、视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)和改良 MacNab 结果。分别在术前和术后以及健康个体中使用疼痛灾难化量表(PCS)和贝克抑郁量表(BDI)评估患者的疼痛灾难性情绪和抑郁的情绪评估。

结果

所有患者年龄在 47 至 85 岁之间,平均年龄为 59.5±9.76 岁。症状持续时间为 114.6±22.77 个月,手术时间为 87.7±25.20 分钟,平均住院时间为 5.8±2.81 天。4 名患者退出,因此共有 76 名患者完成了随访。结果表明,术后 mDCSA 显著改善(<0.001),无论是腰背或下肢的 VAS 或 ODI 均随时间推移而降低(<0.001),术后 2 年内的优秀至良好率从 88.75%提高至 93.42%(<0.05)。5 例患者出现硬脑膜撕裂、神经根或感觉异常等并发症,经保守治疗后均恢复。术后疼痛灾难化评分降低(<0.001),但患者与健康对照组之间 BDI 无显著差异(>0.05)。

结论

“U”形 PELD 似乎是治疗 LSS 合并 DH 的一种替代方法,可达到更好的减压效果,有效改善慢性疼痛状况。但是,仍存在潜在并发症,需要进一步考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/168e/7837780/20e4d1fd4290/PRM2021-6657463.001.jpg

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