Department of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Chem Commun (Camb). 2021 Mar 7;57(19):2368-2371. doi: 10.1039/d0cc08033k. Epub 2021 Feb 3.
Selective 1D TOCSY is a powerful tool in the assignment of NMR spectra of organic molecules. Here an order of magnitude improvement in selectivity, allowing overlapping multiplets to be excited separately, is achieved in a single scan using the very recent GEMSTONE method. The new experiment is illustrated using an antibiotic and a mixture of diastereomers.
选择性 1D TOCSY 是有机分子 NMR 谱分配的有力工具。这里使用最近的 GEMSTONE 方法在单个扫描中实现了选择性的数量级改进，允许单独激发重叠的多重峰。新实验使用抗生素和非对映异构体混合物进行了说明。
