Department of Spine Surgery, Shandong Provincial Hospital affiliated to Shandong First Medical University, No. 9677, Jingshi Road, Jinan, Shandong Province, China.
The Base of Achievement Transformation, Medical Crossover Innovation Institute, University of Shanghai for Science and Technology, Shanghai, China.
Eur Spine J. 2021 Sep;30(9):2457-2466. doi: 10.1007/s00586-021-06749-9. Epub 2021 Feb 3.
This study aimed to investigate the relationship between pelvic incidence and sagittal spinal morphology in Lenke 5 adolescent idiopathic scoliosis (AIS) and its impact on the proximal junctional kyphosis rate after surgery.
The study enrolled a total of 52 cases of Lenke 5 AIS between September 2009 and December 2018. Sagittal spinal morphological parameters, pelvic incidence (PI) and the proximal junctional angle were measured on full-length spinal standing lateral x-ray films preoperatively, postoperatively and at the final follow-up. Pearson correlation analysis was performed to reveal the relationship between sagittal spinal morphology and PI. Multivariable regression analysis and receiver operating characteristic (ROC) curve analysis were performed to identify the risk factors for proximal junctional kyphosis (PJK).
A correlation was found between PI and sagittal spinal morphological parameters, but not between PI and lumbar lordosis. The PJK rate after surgery was 23% (12/52). PI was revealed as an independent risk factor for proximal junctional kyphosis according to multivariable regression analysis (OR = 0.902, p = 0.049). Both multivariable regression analysis and ROC curve analysis verified that restoring a rational postoperative PI-LL/PLL relationship reduced the rate of PJK, including PI-LL mismatch (OR = 0.743, p = 0.046; cutoff value = - 15.5°), the LL-PI ratio (OR = 5.756, p = 0.021; cutoff value = 1.09), and the PLL-PI ratio (OR = 2.116, p = 0.016; cutoff value = 0.40).
PI influences sagittal spinal morphology in Lenke 5 AIS, although it does not show an inherent relationship with lumbar lordosis. PI also correlates to the PJK rate after surgery. Restoring an ideal postoperative PI-LL relationship could decrease the PJK rate.
本研究旨在探讨骨盆入射角(PI)与 Lenke 5 型青少年特发性脊柱侧凸(AIS)矢状位脊柱形态之间的关系,及其对术后近端交界区后凸(PJK)发生率的影响。
回顾性分析 2009 年 9 月至 2018 年 12 月期间接受手术治疗的 52 例 Lenke 5 型 AIS 患者的临床资料。术前、术后及末次随访时均拍摄全脊柱站立位侧位 X 线片,测量矢状位脊柱形态参数、PI 和近端交界区角度。采用 Pearson 相关分析揭示矢状位脊柱形态与 PI 之间的关系。采用多变量回归分析和受试者工作特征(ROC)曲线分析来识别 PJK 的危险因素。
PI 与矢状位脊柱形态参数相关,但与腰椎前凸角(LL)无关。术后 PJK 发生率为 23%(12/52)。多变量回归分析显示,PI 是术后发生 PJK 的独立危险因素(OR=0.902,p=0.049)。多变量回归分析和 ROC 曲线分析均证实,恢复合理的术后 PI-LL/PI 比值可降低 PJK 发生率,包括 PI-LL 不匹配(OR=0.743,p=0.046;截点值=-15.5°)、LL-PI 比值(OR=5.756,p=0.021;截点值=1.09)和 PLL-PI 比值(OR=2.116,p=0.016;截点值=0.40)。
PI 影响 Lenke 5 型 AIS 的矢状位脊柱形态,尽管它与 LL 无固有关系。PI 还与术后 PJK 发生率相关。恢复理想的术后 PI-LL 关系可降低 PJK 发生率。