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腹腔镜胰体尾切除术的实施和培训:来自大容量中心的 23 年经验。

Implementation and training with laparoscopic distal pancreatectomy: 23-year experience from a high-volume center.

机构信息

The Intervention Centre, Rikshospitalet, Oslo University Hospital, Oslo, Norway.

Department of Research & Development, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.

出版信息

Surg Endosc. 2022 Jan;36(1):468-479. doi: 10.1007/s00464-021-08306-3. Epub 2021 Feb 3.

DOI:10.1007/s00464-021-08306-3
PMID:33534075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8741682/
Abstract

BACKGROUND

Distal pancreatectomy is the most common procedure in minimally-invasive pancreatic surgery. Data in the literature suggest that the learning curve flattens after performing up to 30 procedures. However, the exact number remains unclear.

METHODS

The implementation and training with laparoscopic distal pancreatectomy (LDP) in a high-volume center were studied between 1997 and 2020. Perioperative outcomes and factors related to conversion were assessed. The individual experiences of four different surgeons (pioneer and adopters) performing LDP on a regular basis were examined.

RESULTS

Six hundred forty LDPs were done accounting for 95% of all distal pancreatectomies performed throughout the study period. Conversion was needed in 14 (2.2%) patients due to intraoperative bleeding or tumor adherence to the major vasculature. Overall morbidity and mortality rates were 35 and 0.6%, respectively. Intra- and postoperative outcomes did not change for any of the surgeons within their first 40 cases. Operative time significantly decreased after the first 80 cases for the pioneer surgeon and did not change afterwards although the proportion of ductal adenocarcinoma increased. Tumor size increased after the first 80 cases for the first adopter without affecting the operative time.

CONCLUSIONS

In this nearly unselected cohort, no significant changes in surgical outcomes were observed throughout the first 40 LDPs for different surgeons. The exact number of procedures required to overcome the learning curve is difficult to determine as it seems to depend on patient selection policy and specifics of surgical training at the corresponding center.

摘要

背景

胰体尾切除术是微创胰腺手术中最常见的术式。文献中的数据表明,在完成 30 例左右的手术之后,学习曲线趋于平稳。但具体的例数仍不明确。

方法

本研究在 1997 年至 2020 年间对一家高容量中心实施腹腔镜胰体尾切除术(LDP)的情况和培训进行了研究。评估了围手术期结果和与中转相关的因素。研究了四位常规进行 LDP 的不同外科医生(先驱者和接受者)的个人经验。

结果

共完成了 644 例 LDP,占整个研究期间所有胰体尾切除术的 95%。由于术中出血或肿瘤与大血管粘连,有 14 例(2.2%)患者需要中转开腹。总的并发症发生率和死亡率分别为 35%和 0.6%。在他们的前 40 例手术中,没有任何一位外科医生的术中及术后结果发生变化。对于先驱者外科医生,手术时间在完成前 80 例后显著减少,尽管之后管状腺癌的比例增加,但之后没有变化。对于第一个接受者,肿瘤大小在完成前 80 例后增加,但手术时间没有变化。

结论

在本几乎未选择的队列中,不同外科医生在完成前 40 例 LDP 期间,手术结果没有明显变化。克服学习曲线所需的手术例数很难确定,因为它似乎取决于患者选择政策和相应中心的手术培训特点。

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本文引用的文献

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Comparison of the duration of hospital stay after laparoscopic or open distal pancreatectomy: randomized controlled trial.腹腔镜与开腹胰体尾切除术住院时间的比较:随机对照试验。
Br J Surg. 2020 Sep;107(10):1281-1288. doi: 10.1002/bjs.11554. Epub 2020 Apr 7.
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The Miami International Evidence-based Guidelines on Minimally Invasive Pancreas Resection.《迈阿密微创胰腺切除术循证指南》。
Ann Surg. 2020 Jan;271(1):1-14. doi: 10.1097/SLA.0000000000003590.
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Multicentre observational cohort study of implementation and outcomes of laparoscopic distal pancreatectomy.腹腔镜胰体尾切除术的实施和结果的多中心观察性队列研究。
Br J Surg. 2019 Nov;106(12):1657-1665. doi: 10.1002/bjs.11292. Epub 2019 Aug 27.
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Minimally Invasive Versus Open Distal Pancreatectomy (LEOPARD): A Multicenter Patient-blinded Randomized Controlled Trial.微创与开腹远端胰腺切除术(LEOPARD):一项多中心患者盲法随机对照试验。
Ann Surg. 2019 Jan;269(1):2-9. doi: 10.1097/SLA.0000000000002979.
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True learning curve of laparoscopic spleen-preserving distal pancreatectomy with splenic vessel preservation.腹腔镜保留脾脏的胰体尾切除术及脾血管保留的真实学习曲线。
Surg Endosc. 2019 Jan;33(1):88-93. doi: 10.1007/s00464-018-6277-y. Epub 2018 Jun 22.
6
Laparoscopic distal pancreatectomy: which factors are related to open conversion? Lessons learned from 68 consecutive procedures in a high-volume pancreatic center.腹腔镜胰体尾切除术:哪些因素与中转开腹相关?在一个高容量的胰腺中心连续 68 例手术中获得的经验教训。
Surg Endosc. 2018 Sep;32(9):3839-3845. doi: 10.1007/s00464-018-6113-4. Epub 2018 Feb 12.
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International Summit on Laparoscopic Pancreatic Resection (ISLPR) "Coimbatore Summit Statements".国际腹腔镜胰腺切除术峰会(ISLPR)“哥印拜陀峰会声明”
Surg Oncol. 2018 Mar;27(1):A10-A15. doi: 10.1016/j.suronc.2017.12.001. Epub 2017 Dec 27.
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Assessing the impact of conversion on outcomes of minimally invasive distal pancreatectomy and pancreatoduodenectomy.评估中转对微创远端胰腺切除术和胰十二指肠切除术结局的影响。
HPB (Oxford). 2018 Apr;20(4):356-363. doi: 10.1016/j.hpb.2017.10.007. Epub 2017 Nov 27.
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Preoperative risk factors for conversion and learning curve of minimally invasive distal pancreatectomy.微创远端胰腺切除术中转的术前危险因素及学习曲线
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