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贴脸口罩对眼部附近定量颗粒计数的影响:对 COVID-19 时代眼内注射的启示。

Effect of Taping Face Masks on Quantitative Particle Counts Near the Eye: Implications for Intravitreal Injections in the COVID-19 Era.

机构信息

From the Sidney Kimmel Medical College (WGS, SNP, AEK, AC, SJG, JH), Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Vision Research Center (JES, QZ), Wills Eye Hospital, Thomas Jefferson University, Philadelphia Pennsylvania, USA.

出版信息

Am J Ophthalmol. 2021 May;225:166-171. doi: 10.1016/j.ajo.2021.01.021. Epub 2021 Jan 31.

Abstract

PURPOSE

To determine the effect of taping the top of face masks on air particle counts directed toward the eye during simulated intravitreal injections.

DESIGN

Prospective observational crossover study.

METHODS

Thirteen healthy subjects were recruited. Each wore a cloth, surgical, or N95 mask in randomized order. The number of air particles were quantified by using a particle counter suspended over the right eye while each subject breathed normally, deeply, or spoke using a standardized script. Particle counts were obtained with the top of each mask taped and not taped. The main outcome measurements were particle counts of 0.3, 0.5, 1, 3, 5, and 10 μm and total particle counts.

RESULTS

Taping cloth masks while subjects were speaking significantly reduced particle counts for the 0.3- (P = .03), 0.5- (P = .01), and 1-μm (P = .03) particles and total particle counts (P = .008) compared to no taping. Taping the top of cloth masks during normal or deep breathing did not significantly affect particle counts compared to no taping. Taping the top of surgical or N95 masks did not significantly alter particle counts for any breathing condition tested.

CONCLUSIONS

Taping the top of cloth masks prior to simulated intravitreal injections significantly reduced air particle counts directed toward the eye when subjects were speaking compared to no taping. This may have implications for decreasing air particles reaching the eye during intravitreal injections, including aerosolized droplets from a patient's mouth that may carry oral pathogens.

摘要

目的

确定在模拟玻璃体腔内注射过程中,对面罩顶部进行胶带固定对面部口罩上方朝向眼睛的空气颗粒计数的影响。

设计

前瞻性观察性交叉研究。

方法

招募了 13 名健康受试者。他们随机佩戴布制、外科或 N95 口罩。当每个受试者正常呼吸、深呼吸或使用标准脚本说话时,通过悬浮在右眼上方的粒子计数器来量化空气颗粒数量。在对每个口罩的顶部进行胶带固定和不固定的情况下,分别获得粒子计数。主要观察指标是 0.3、0.5、1、3、5 和 10μm 以及总粒子计数的粒子计数。

结果

与不进行胶带固定相比,当受试者说话时,对布制口罩顶部进行胶带固定可显著减少 0.3-μm(P=0.03)、0.5-μm(P=0.01)和 1-μm(P=0.03)颗粒以及总粒子计数(P=0.008)。与不进行胶带固定相比,在正常呼吸或深呼吸期间对布制口罩顶部进行胶带固定不会显著影响粒子计数。对任何测试的呼吸条件,对手术或 N95 口罩顶部进行胶带固定都不会显著改变粒子计数。

结论

在模拟玻璃体腔内注射前对面罩顶部进行胶带固定,与不进行胶带固定相比,当受试者说话时,可显著减少朝向眼睛的空气颗粒计数。这可能对减少玻璃体腔内注射过程中到达眼睛的空气颗粒具有重要意义,包括来自患者口腔的气溶胶化飞沫可能携带口腔病原体。

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