Garg Sunir J, Dollin Michael, Hsu Jason, Storey Philip, Vander James F
Ophthalmic Surg Lasers Imaging Retina. 2015 Nov-Dec;46(10):1028-34. doi: 10.3928/23258160-20151027-07.
To report the effect of a "no-talking" policy during intravitreal injection (IVI) on post-injection endophthalmitis.
Retrospective, comparative, consecutive case series of patients receiving IVI between Jan. 1, 2009, and Dec. 31, 2012. A 24-month "usual care" period was compared to a 24-month no-talking period, during which a strategy to further minimize speech during IVI was implemented.
During the usual care period, 47,155 IVIs were performed, with nine culture-positive cases (0.019%), including seven due to oral pathogens (0.015%). During the no-talking period, 82,658 IVIs were performed, with eight culture-positive cases (0.010%), including two due to oral pathogens (0.002%). The no-talking policy was associated with a decreased endophthalmitis risk (P = .004), including oral pathogen-associated endophthalmitis (P = .02).
This study demonstrates that a more stringent no-talking policy during IVI may reduce the risk of post-injection endophthalmitis.
报告玻璃体内注射(IVI)期间“禁止交谈”政策对注射后眼内炎的影响。
对2009年1月1日至2012年12月31日期间接受IVI的患者进行回顾性、对比性、连续性病例系列研究。将24个月的“常规护理”期与24个月的“禁止交谈”期进行比较,在“禁止交谈”期实施了一项在IVI期间进一步减少言语的策略。
在常规护理期,共进行了47,155次IVI,有9例培养阳性病例(0.019%),其中7例由口腔病原体引起(0.015%)。在“禁止交谈”期,共进行了82,658次IVI,有8例培养阳性病例(0.010%),其中2例由口腔病原体引起(0.002%)。“禁止交谈”政策与眼内炎风险降低相关(P = 0.004),包括与口腔病原体相关的眼内炎(P = 0.02)。
本研究表明,在IVI期间实施更严格的“禁止交谈”政策可能会降低注射后眼内炎的风险。