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贡纳尔·荣格纳与疾病筛查的原则和实践

Gunnar Jungner and the Principles and Practice of Screening for Disease.

作者信息

Jungner Lars, Jungner Ingmar, Engvall Martin, Döbeln Ulrika von

机构信息

Son of Gunnar Jungner, Master of Business Administration, University of Stockholm, SE-106 91 Stockholm, Sweden.

Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden.

出版信息

Int J Neonatal Screen. 2017 Aug 21;3(3):23. doi: 10.3390/ijns3030023.

Abstract

We present a biography of Gunnar Jungner, one of the authors of the Principles and Practice of Screening for Disease by JMG Wilson and G Jungner, published by the WHO in 1968. This publication contains ten criteria, which are still consulted, when a new disorder is evaluated for inclusion in a screening program. Gunnar Jungner was a Swedish MD, PhD, specialized in Clinical Chemistry, born in Sweden in 1914. In 1961 he built an automated instrument for the analysis of different components in plasma, with the aim to detect diseases in presumably healthy individuals, to enable start of treatment at an early disease stage. This first automated instrument for Clinical Chemistry in Sweden was used in a screening project, where 90 000 seemingly healthy individuals were included. The study was discussed extensively and he was invited to present the results at different international meetings, where he also met JMG Wilson. Gunnar Jungner developed the instrument further together with his brother Ingmar and the Swedish gas company AGA. The brothers also established an out-patient ward in Stockholm, where people could come for health screening.

摘要

我们介绍贡纳尔·荣格纳的生平。他是《疾病筛查的原则与实践》的作者之一,该书由JMG威尔逊和G·荣格纳合著,1968年由世界卫生组织出版。该出版物包含十条标准,在评估一种新疾病是否纳入筛查项目时仍会被参考。贡纳尔·荣格纳是一位瑞典医学博士、哲学博士,专长于临床化学,1914年出生于瑞典。1961年,他制造了一台用于分析血浆中不同成分的自动化仪器,目的是在看似健康的个体中检测疾病,以便在疾病早期阶段开始治疗。瑞典第一台临床化学自动化仪器被用于一个筛查项目,该项目纳入了9万名看似健康的个体。这项研究得到了广泛讨论,他受邀在不同的国际会议上展示研究结果,在这些会议上他还结识了JMG威尔逊。贡纳尔·荣格纳与他的兄弟英格玛以及瑞典气体公司AGA进一步改进了该仪器。兄弟俩还在斯德哥尔摩设立了一个门诊病房,人们可以前来进行健康筛查。

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