Simonetti Oriana, Molinelli Elisa, Brisigotti Valerio, Brancorsini Donatella, Talevi Davide, Offidani Annamaria
Dermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60126 Ancona, Italy.
Department of Biomedical Sciences, Institute of Pathological Anatomy and Histopathology, Polytechnic University Marche, 60126 Ancona, Italy.
Dermatopathology (Basel). 2021 Feb 1;8(1):29-32. doi: 10.3390/dermatopathology8010005.
Primary dermal melanoma (PDM) is a rare distinct variant of cutaneous melanoma, predominantly occurring on the extremities of young or middle-aged adults. In comparison to conventional melanoma, PDM is characterized by unexpectedly prolonged survival and long-term survival. Thus, correct identification of this variant is crucial to avoid potential misdiagnosis and establish correct treatment and follow-up. In addition, no consensus and specific guidelines exist on the management of this peculiar subtype of cutaneous melanoma.
原发性皮肤黑色素瘤（PDM）是皮肤黑色素瘤中一种罕见的独特变体，主要发生在年轻或中年成年人的四肢。与传统黑色素瘤相比，PDM的特点是生存期意外延长和长期存活。因此，正确识别这种变体对于避免潜在的误诊以及确立正确的治疗和随访至关重要。此外，对于这种特殊类型的皮肤黑色素瘤的管理，目前尚无共识和具体指南。
