Arends J P, Zanen H C
Netherlands Reference Laboratory for Bacterial Meningitis, Academic Medical Center, Amsterdam.
Rev Infect Dis. 1988 Jan-Feb;10(1):131-7. doi: 10.1093/clinids/10.1.131.
Between 1968 and 1984, 30 strains of Streptococcus suis causing meningitis were isolated in the Netherlands. Twenty-eight strains were type 2, one was type 4, and one was untypable. The average age of the patients infected with these strains was 49 years (range, 21-76 years); the male-to-female ratio was 6.5. Twenty-five patients (83%) were employed in the pork industry. Two patients (7%) died. In seven cases (23%), predisposing factors were identified. The most frequent sequela was hearing loss (54% of surviving patients). The data for these 30 patients were compared with those for 30 patients from outside the Netherlands whose cases of meningitis due to S. suis type 2 were described between 1968 and 1985. No differences were found. The estimated annual risk of developing S. suis meningitis among Dutch abattoir workers and pig breeders was approximately 3.0/100,000--a rate 1,500 times higher than that among persons not working in the pork industry.
1968年至1984年间，荷兰分离出30株引起脑膜炎的猪链球菌。28株为2型，1株为4型，1株无法分型。感染这些菌株的患者平均年龄为49岁（范围21 - 76岁）；男女比例为6.5。25名患者（83%）从事猪肉行业。2名患者（7%）死亡。7例（23%）发现有诱发因素。最常见的后遗症是听力丧失（存活患者的54%）。将这30例患者的数据与1968年至1985年间描述的30例荷兰以外因2型猪链球菌引起脑膜炎的患者的数据进行比较，未发现差异。荷兰屠宰场工人和养猪户中发生猪链球菌脑膜炎的估计年风险约为3.0/10万，这一发病率比不在猪肉行业工作的人高1500倍。
