Sishuba Anathi, Leboko Jessica, Ateba Collins Njie, Manganyi Madira Coultyne
Department of Microbiology, North West University - Mafikeng Campus, Mmabatho, South Africa.
Mycobiology. 2021 Jan 12;49(1):89-94. doi: 10.1080/12298093.2020.1857009.
Forty-three ( = 43) endophytic fungi with different morphologic characteristics were from a medicinal plant were utilized to investigate their antifungal effectiveness against pathogenic fungi. All fungal isolates exhibited antifungal activity against one or more pathogens in the dual culture test whereas only 33 fungal culture filtrates (77%) showed decent antifungal effect. and were the dominate genus that displayed significant antifungal activity. Isolates GG02, GG09, ND15, and ND17 showed the broadest spectrum of antifungal activity. Furthermore, culture filtrate of Fusarium sp. DR08 exhibited a broad range of antifungal activity against all the pathogens. The results suggest endophytic fungi isolated from medicinal plant might be a source of novel bioactive molecules. To the best our knowledge, this is the first report on endophytic fungi isolated from native kougoed exhibiting antifungal activity against plant fungal pathogens.
从一种药用植物中分离出43株具有不同形态特征的内生真菌，用于研究它们对致病真菌的抗真菌效果。在双培养试验中，所有真菌分离株均对一种或多种病原体表现出抗真菌活性，而只有33份真菌培养滤液（77%）显示出良好的抗真菌效果。青霉属和镰孢属是显示出显著抗真菌活性的主要属。分离株GG02、GG09、ND15和ND17表现出最广谱的抗真菌活性。此外，镰孢菌属DR08的培养滤液对所有病原体都表现出广泛的抗真菌活性。结果表明，从药用植物中分离出的内生真菌可能是新型生物活性分子的来源。据我们所知，这是关于从本土苦茄中分离出的内生真菌对植物真菌病原体具有抗真菌活性的首次报道。
