Jacobsen Laura Kjær, Haslund Helle, Brock Christina, Laursen Birgitte Schantz
Clinical Nursing Research Unit, Aalborg University Hospital, Aalborg, Denmark.
Clinic of Anesthesia, Children, Circuits and Women, Aalborg University Hospital, Aalborg, Denmark.
Eur J Midwifery. 2018 Nov 16;2:15. doi: 10.18332/ejm/99545. eCollection 2018.
Approximately 25% of all deliveries in Denmark are medically induced, typically characterized by more intense uterine contractions. The aim of this paper is to investigate the differences in the administration of epidural analgesia and pain experience between spontaneous and medically induced labor in nulliparous and multiparous women.
This is a prospective case-controlled study of 100 participating women in labor. The primary outcome was the timing of administration of epidural analgesia, by delivery progression and frequency. Pain scores were indicated by the McGill Pain Questionnaire and the duration of pain was also notified.
In nulliparous and multiparous women, medically induced labor was associated with earlier administration of epidural analgesia in relation to the onset of labor pain, compared to women with a spontaneous onset of labor (10.4 vs 26.10 hours, p=0.0). There was a trend, however not statistical, in the use of epidural analgesia in relation to delivery progression, assessed as dilation of the cervix (3 cm vs 4.5 cm, p=0.07) and towards higher frequency for medically induced labor (51.5% vs 32.8%, p=0.07). In nulliparous women, a reduced period of labor pain was shown in medically induced deliveries compared to spontaneous deliveries (9.30 vs 19.00 hours, p=0.03). However, no significant differences in experienced pain were shown (Score: 28.70 vs 29.60, p=0.194).
Epidural analgesia was administered earlier, and duration of experienced pain was shorter in medically induced labor, in comparison to spontaneous deliveries. However, the experienced pain was not different, possibly explained by a more intense labor process.
在丹麦,约25%的分娩是医学引产,其特点通常是子宫收缩更强烈。本文旨在研究初产妇和经产妇自然分娩与医学引产在硬膜外镇痛给药和疼痛体验方面的差异。
这是一项对100名参与分娩的妇女进行的前瞻性病例对照研究。主要结局是根据分娩进展和频率确定硬膜外镇痛的给药时间。疼痛评分通过麦吉尔疼痛问卷表示,同时也记录疼痛持续时间。
与自然发动分娩的妇女相比,初产妇和经产妇中,医学引产与分娩疼痛发作后更早给予硬膜外镇痛相关(10.4小时对26.10小时,p = 0.0)。然而,在根据宫颈扩张评估的分娩进展方面,硬膜外镇痛的使用存在一种趋势但无统计学意义(3厘米对4.5厘米,p = 0.07),且医学引产的使用频率更高(51.5%对32.8%,p = 0.07)。在初产妇中,医学引产分娩的产痛时间比自然分娩缩短(9.30小时对19.00小时,p = 0.03)。然而,在疼痛体验方面未显示出显著差异(评分:28.70对29.60,p = 0.194)。
与自然分娩相比,医学引产时硬膜外镇痛给药更早,疼痛持续时间更短。然而,疼痛体验并无差异,这可能是由于产程更强烈所致。