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大枕神经阻滞改善慢性偏头痛患者睡眠质量的临床疗效:一项前瞻性观察研究。

Clinical success of greater occipital nerve blockade in improving sleep quality of chronic migraineurs: a prospective observational study.

机构信息

Department of Neurology, School of Medicine, Yozgat Bozok University, Erdogan Akdag Campus, Ataturk Road 7. Km, 66100, Yozgat, Turkey.

Neurology Clinic, Ministry of Health Ankara Research and Training Hospital, 06230, Ankara, Turkey.

出版信息

Sleep Breath. 2021 Jun;25(2):1003-1010. doi: 10.1007/s11325-021-02309-z. Epub 2021 Feb 3.

Abstract

BACKGROUND

The success of various therapy methods in the treatment of insomnia and poor quality sleep, both of which play an active role in the chronicization process of migraine, has been the subject of investigation. The aim of this research was to evaluate the success, acceptability, and efficacy of greater occipital nerve block (GON-B) therapy in chronic migraine (CM) patients in improving their sleep quality and developing their beliefs about sleep .

METHODS

The study included 40 patients with CM from the general population who agreed to receive blockade therapy. Before the injection treatment, 1-week sleep diaries as well as depression and anxiety symptoms were examined. The Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Pre-Sleep Arousal Scale (PSAS), Epworth Sleepiness Scale (ESS), and Dysfunctional Beliefs and Attitudes about Sleep (DBAS) scales were measured and evaluated both before and after the completion of 3 months of treatment.

RESULTS

Thirty-seven patients with CM successfully completed our 12-week treatment period. The anxiety and depression scales of the patients decreased after 3 months (p < 0.001). PSQI and its subgroups ratings significantly improved after treatment (p < 0.001). Similarly, ISI, ESS, PSAS, and DBAS test scores also improved after treatment (p < 0.001).

CONCLUSIONS

This study provides evidence as to the applicability and acceptability of GON-B in CM treatment in terms of increased sleep quality; improved sleep beliefs, attitudes, and behaviors; and arousals and decreased insomnia findings.

摘要

背景

各种治疗方法在治疗失眠和睡眠质量差方面的成功,这两者在偏头痛的慢性化过程中都起着积极的作用,这已经成为研究的主题。本研究旨在评估枕大神经阻滞(GON-B)治疗慢性偏头痛(CM)患者改善睡眠质量和睡眠信念的疗效、可接受性。

方法

本研究纳入了 40 名来自普通人群的 CM 患者,他们同意接受阻滞治疗。在注射治疗前,检查了 1 周的睡眠日记以及抑郁和焦虑症状。在完成 3 个月的治疗后,使用匹兹堡睡眠质量指数(PSQI)、失眠严重程度指数(ISI)、睡前觉醒量表(PSAS)、Epworth 嗜睡量表(ESS)和睡眠功能障碍信念和态度量表(DBAS)进行了测量和评估。

结果

37 名 CM 患者成功完成了我们 12 周的治疗期。治疗 3 个月后,患者的焦虑和抑郁量表评分下降(p<0.001)。PSQI 及其亚组评分在治疗后显著改善(p<0.001)。同样,ISI、ESS、PSAS 和 DBAS 测试评分在治疗后也有所改善(p<0.001)。

结论

本研究提供了证据,证明 GON-B 在 CM 治疗中的适用性和可接受性,可提高睡眠质量;改善睡眠信念、态度和行为;减少觉醒和失眠发现。

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