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翼状胬肉单独接受 Yttrium-90/Strontium-90 射线照射后角膜生物力学特性的变化。

Changes of Corneal Biomechanical Properties upon Exclusive Ytt-/Sr-90 Irradiation of Pterygium.

机构信息

Eye Clinic Orasis, Swiss Eye Research Foundation, 5734 Reinach AG, Switzerland.

Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, 3012 Bern, Switzerland.

出版信息

Sensors (Basel). 2021 Feb 2;21(3):975. doi: 10.3390/s21030975.

DOI:10.3390/s21030975
PMID:33540506
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7867194/
Abstract

BACKGROUND

It is known that pterygia above a certain size cause astigmatism and other aberrations of the human cornea and thus impair the quality of vision. Exclusive Sr-/Ytt-90 beta irradiation is a highly effective treatment for primary pterygia. The aim of this retrospective study is to determine the extent to which higher order corneal aberrations are affected by this treatment.

METHODS

Evaluation of corneal topographies and wavefront aberration data of 20 primary pterygia patients generated before and at different points in time in the first year after irradiation. Additionally, the size of the pterygium was measured.

RESULTS

The study showed a significant increase in coma and triple leaf aberrations in pterygia with a horizontal length of 2 mm and more. It was also found that a pterygium size greater than 2 mm significantly induces astigmatism. Both phenomena reduce visual quality. In none of the patients could a pterygium recurrence be detected after irradiation.

CONCLUSIONS

If the pterygium size is less than 2 mm, early exclusive Sr/Ytt-90 beta irradiation can be recommended. If the size is more than 2 mm, a pterygium excision 6 months after beta irradiation can be discussed.

摘要

背景

众所周知,超过一定大小的翼状胬肉会导致人眼角膜散光和其他像差,从而损害视力质量。单纯的 Sr-/Ytt-90β射线辐射是治疗原发性翼状胬肉的一种非常有效的方法。本回顾性研究旨在确定这种治疗方法对高阶角膜像差的影响程度。

方法

评估了 20 名原发性翼状胬肉患者的角膜地形图和波前像差数据,这些数据是在照射前以及照射后第一年的不同时间点生成的。此外,还测量了翼状胬肉的大小。

结果

研究表明,水平长度为 2 毫米及以上的翼状胬肉中彗差和三叶像差明显增加。还发现,翼状胬肉大小大于 2 毫米会显著导致散光。这两种现象都会降低视觉质量。在所有患者中,照射后均未发现翼状胬肉复发。

结论

如果翼状胬肉的大小小于 2 毫米,可以推荐早期进行单纯 Sr/Ytt-90β射线辐射治疗。如果大小大于 2 毫米,可以考虑在β射线辐射后 6 个月进行翼状胬肉切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/43e49afff7df/sensors-21-00975-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/b8f3ba39d869/sensors-21-00975-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/43e49afff7df/sensors-21-00975-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/b8f3ba39d869/sensors-21-00975-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/b6e048182ba3/sensors-21-00975-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/db2334432ee9/sensors-21-00975-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/fc27630c21d6/sensors-21-00975-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/a79a3977243b/sensors-21-00975-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/6c6326ffb78c/sensors-21-00975-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a522/7867194/43e49afff7df/sensors-21-00975-g009.jpg

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本文引用的文献

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Corneal aberrations measured with a high-resolution Scheimpflug tomographer: repeatability and reproducibility.采用高分辨率 Scheimpflug 断层扫描仪测量角膜像差:可重复性和再现性。
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Pterygium Is Related to Short Axial Length.翼状胬肉与短眼轴长度有关。
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Influence of pterygium size on corneal higher-order aberration evaluated using anterior-segment optical coherence tomography.
使用眼前节光学相干断层扫描评估翼状胬肉大小对角膜高阶像差的影响。
BMC Ophthalmol. 2018 Jul 9;18(1):166. doi: 10.1186/s12886-018-0837-8.
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A Comparative Study of Higher order Aberrations between Pterygium and Non-Pterygium Eyes.翼状胬肉与非翼状胬肉眼高阶像差的比较研究
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Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study.翼状胬肉放射外科的生物力学建模:一项回顾性病例研究。
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