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阿曼的眼内炎:一项描述性回顾性多中心研究。

Endophthalmitis in Oman: A descriptive retrospective multi-center study.

作者信息

Al-Abri Mohamed, Al-Hinai Ahmed, Al Hamar Youssef, Al-Abri Hisham, Habsi Asaad-Al, Al-Kaabi Abdullah, Nooyi Chandrashekar

机构信息

Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman.

Department of Ophthalmology, Al Nahdha Hospital, Ministry of Health, Muscat, Sultanate of Oman.

出版信息

Oman J Ophthalmol. 2020 Nov 2;13(3):141-145. doi: 10.4103/ojo.OJO_249_2020. eCollection 2020 Sep-Dec.

DOI:10.4103/ojo.OJO_249_2020
PMID:33542602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7852418/
Abstract

PURPOSE

The aim of this study is to report the anatomical and functional outcome, microbiology profile and treatment used for endophthalmitis in Oman.

DESIGN

The study design involves retrospective descriptive multicenter study.

METHODS

Demographic and clinical data of patients diagnosed with endophthalmitis over a period of 9 years were collected in three tertiary hospitals in Oman.

RESULTS

A total of 50 endophthalmitis cases were included in the study. Exogenous endophthalmitis was diagnosed in 48 cases, whereas 2 cases were endogenous endophthalmitis. Culture-positive cases constituted 16 cases (32%) out of these, 12 cases were Gram-positive, 3 cases were Gram-negative and one case had a positive fungal culture. Immediate first-line treatment was vitreous tap and inject in 33 eyes and vitrectomy in 13 eyes. In 45 eyes in which the visual acuity (VA) was recorded; VA after treatment improved in 22 eyes (49%), remained the same in 16 eyes (36%) and worsened in 7 eyes (16%).

CONCLUSION

Although endophthalmitis is rare, it is a devastating ocular emergency. Early diagnosis and prompt intervention are crucial in management. Awareness among the patients undergoing intraocular surgeries about this rare condition is very crucial. Moreover, frontline health-care providers must be aware and critical if they encounter patients with suspicion of endophthalmitis as early recognition, prompt referral, and timely treatment are the key for better visual prognosis. Finally, establishing a National Endophthalmitis Registry is recommended as it will help analyze the incidence, treatment instituted and the outcome of this condition across Oman.

摘要

目的

本研究旨在报告阿曼眼内炎的解剖和功能结果、微生物学特征及治疗方法。

设计

本研究设计为回顾性描述性多中心研究。

方法

收集阿曼三家三级医院9年间诊断为眼内炎患者的人口统计学和临床数据。

结果

本研究共纳入50例眼内炎病例。其中48例诊断为外源性眼内炎,2例为内源性眼内炎。这些病例中培养阳性的有16例(32%),其中12例为革兰氏阳性菌,3例为革兰氏阴性菌,1例真菌培养阳性。一线即刻治疗中,33只眼行玻璃体穿刺注药,13只眼行玻璃体切除术。记录了45只眼的视力;治疗后视力改善的有22只眼(49%),16只眼(36%)视力不变,7只眼(16%)视力恶化。

结论

尽管眼内炎罕见,但却是一种严重的眼部急症。早期诊断和及时干预对治疗至关重要。接受眼内手术的患者对这种罕见疾病的认知非常关键。此外,一线医护人员在遇到疑似眼内炎患者时必须保持警惕,因为早期识别、及时转诊和及时治疗是改善视力预后的关键。最后,建议建立全国眼内炎登记处,这将有助于分析阿曼各地这种疾病的发病率、治疗方法及结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751b/7852418/6f54815ad7a5/OJO-13-141-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751b/7852418/6f54815ad7a5/OJO-13-141-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751b/7852418/6f54815ad7a5/OJO-13-141-g001.jpg

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Clin Ophthalmol. 2015 Jan 8;9:95-108. doi: 10.2147/OPTH.S76406. eCollection 2015.
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FRIENDS Group: clinical and microbiological characteristics of post-filtering surgery endophthalmitis.FRIENDS 组:过滤术后眼内炎的临床和微生物学特征。
Graefes Arch Clin Exp Ophthalmol. 2014 Jan;252(1):101-7. doi: 10.1007/s00417-013-2503-4. Epub 2013 Nov 19.
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Endophthalmitis: Pathogenesis, clinical presentation, management, and perspectives.眼内炎:发病机制、临床表现、治疗及展望
Clin Ophthalmol. 2010 Mar 24;4:121-35. doi: 10.2147/opth.s6461.
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Exogenous fungal endophthalmitis: microbiology and clinical outcomes.外源性真菌性眼内炎:微生物学与临床结局
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