眼内炎：发病机制、临床表现、治疗及展望
Endophthalmitis: Pathogenesis, clinical presentation, management, and perspectives.
作者信息
Kernt M, Kampik A
机构信息
Department of Ophthalmology, Ludwig Maximilian University, Munich, Germany.
出版信息
Clin Ophthalmol. 2010 Mar 24;4:121-35. doi: 10.2147/opth.s6461.
Abstract
Endophthalmitis is a rare but sight-threatening complication that can occur after ocular surgery or trauma or as a consequence of systemic infection. To optimize visual outcome, early diagnosis and treatment are essential. Over recent decades, advances in hygienic standards, improved microbiologic and surgical techniques, development of powerful antimicrobial drugs, and the introduction of intravitreal antibiotic therapy have led to a decreased incidence and improved management of endophthalmitis. However, endophthalmitis still represents a serious clinical problem. This review focuses on current principles and techniques for evaluation and treatment of endophthalmitis. In addition, it addresses recent developments regarding antimicrobial treatment and prophylaxis of infectious endophthalmitis.
摘要
眼内炎是一种罕见但可威胁视力的并发症，可发生于眼科手术或外伤后，或作为全身感染的结果。为优化视觉预后，早期诊断和治疗至关重要。近几十年来，卫生标准的提高、微生物学和手术技术的改进、强效抗菌药物的研发以及玻璃体内抗生素治疗的引入，已使眼内炎的发病率降低，管理得到改善。然而，眼内炎仍然是一个严重的临床问题。本综述重点关注眼内炎评估和治疗的当前原则与技术。此外，还讨论了感染性眼内炎抗菌治疗和预防方面的最新进展。
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