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一例艾司洛尔导致苯丙胺尿液药物检测假阳性的病例。

A Case of Esmolol-Induced False-Positive Amphetamine Urine Drug Test.

作者信息

Adashek Jacob J, Khadilkar Arjun, Enciso Juan, Rane Rishi, Wu Robby

机构信息

Internal Medicine, University of South Florida (USF) Health, Tampa, USA.

Emergency Medicine, University of South Florida (USF) Health, Tampa, USA.

出版信息

Cureus. 2021 Jan 2;13(1):e12429. doi: 10.7759/cureus.12429.

DOI:10.7759/cureus.12429
PMID:33542876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7849827/
Abstract

False-positive urine drug screens can occur and lead to implicit bias. Confirmatory testing with gas chromatography/mass spectrometry can be performed. A morbidly obese patient with newly diagnosed atrial fibrillation spent multiple days in the cardiac intensive care unit (ICU) due to a false-positive test for methamphetamine. The patient was planned to undergo direct cardioversion with conscious-sedation anesthesia. His care was delayed because anesthesia was not comfortable administering sedatives in the setting of a positive urine drug screen for presumed methamphetamine use. Knowing that esmolol can cause a false positive on urine drug screen is imperative for delivering the best patient-centered care.

摘要

尿液药物筛查可能会出现假阳性结果,并导致隐性偏见。可采用气相色谱/质谱法进行确证检测。一名新诊断为房颤的病态肥胖患者因甲基苯丙胺检测呈假阳性,在心脏重症监护病房(ICU)住了好几天。该患者计划在清醒镇静麻醉下进行直接心脏复律。由于在假定使用甲基苯丙胺的尿液药物筛查呈阳性的情况下,麻醉医生对给予镇静剂感到不安,导致他的治疗被推迟。了解艾司洛尔会导致尿液药物筛查出现假阳性结果,对于提供以患者为中心的最佳护理至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8310/7849827/7e89b385ff7d/cureus-0013-00000012429-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8310/7849827/308a313cbbb2/cureus-0013-00000012429-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8310/7849827/7e89b385ff7d/cureus-0013-00000012429-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8310/7849827/308a313cbbb2/cureus-0013-00000012429-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8310/7849827/7e89b385ff7d/cureus-0013-00000012429-i02.jpg

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本文引用的文献

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Urine Drug Tests: Ordering and Interpreting Results.尿液药物检测:检测申请与结果解读。
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Obstructive Sleep Apnea as a Risk Factor for Atrial Fibrillation: A Meta-Analysis.阻塞性睡眠呼吸暂停作为心房颤动的一个危险因素:一项荟萃分析。
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Clinical Interpretation of Urine Drug Tests: What Clinicians Need to Know About Urine Drug Screens.尿液药物检测的临床解读:临床医生需要了解的尿液药物筛查知识
Mayo Clin Proc. 2017 May;92(5):774-796. doi: 10.1016/j.mayocp.2016.12.007. Epub 2017 Mar 18.
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Case Rep Cardiol. 2016;2016:2343691. doi: 10.1155/2016/2343691. Epub 2016 Aug 8.
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