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Anatomage 表在检测头颈癌结外侵犯中的准确性:一项初步研究。

Accuracy of the Anatomage Table in detecting extranodal extension in head and neck cancer: a pilot study.

作者信息

Tirelli Giancarlo, de Groodt Jasmina, Sia Egidio, Belgrano Manuel Gianvalerio, Degrassi Ferruccio, Boscolo-Rizzo Paolo, Cova Maria Assunta, Marcuzzo Alberto Vito

机构信息

Azienda Sanitaria Universitaria Giuliano Isontina-ENT Clinic, Trieste, Italy.

Unit of Diagnostic and Interventional Radiology, Cattinara Hospital, ASUGI, Trieste, Italy.

出版信息

J Med Imaging (Bellingham). 2021 Jan;8(1):014502. doi: 10.1117/1.JMI.8.1.014502. Epub 2021 Feb 1.

Abstract

: To assess whether the three-dimensional reconstructions of preoperative computed tomography (CT) scans are helpful for establishing extranodal extension (ENE) in head and neck carcinoma. : Patients with a histological diagnosis of ENE ( ) were considered "cases" and patients with negative histological examination for ENE ( ) were considered "controls." Cases and controls were divided into two groups: a major nodes (MaN) group (lymph nodes on ) and a minor nodes (MiN) group (lymph nodes on ). The preoperative CT scans were uploaded to the Anatomage Table and were randomly and blindly provided to the radiologist for assessment. The findings at the Anatomage Table were compared with those of CT and magnetic resonance imaging (MRI) scans. : Analysis of data from the MaN group showed that the Anatomage Table had a higher percentage of concordance with histopathological examination (90%) than the CT and MRI scans. The Anatomage Table had 100% sensitivity in identifying all patients, associated with a lower specificity. The negative predictive value of 100% allowed identification of patients. In the MiN group, on the other hand, sensitivity was lower, related to a high number of false-negative results. : The Anatomage Table could represent a useful tool for preoperatively establishing the extranodal extension of cervical lymph node metastasis.

摘要

评估术前计算机断层扫描(CT)的三维重建是否有助于确定头颈癌的结外扩展(ENE)。将组织学诊断为ENE( )的患者视为“病例组”,组织学检查ENE为阴性( )的患者视为“对照组”。病例组和对照组分为两组:主要淋巴结(MaN)组( 上的淋巴结)和次要淋巴结(MiN)组( 上的淋巴结)。将术前CT扫描上传至Anatomage Table,并随机且盲法提供给放射科医生进行评估。将Anatomage Table上的结果与CT和磁共振成像(MRI)扫描结果进行比较。MaN组的数据分析表明,Anatomage Table与组织病理学检查的一致性百分比(90%)高于CT和MRI扫描。Anatomage Table在识别所有 患者时具有100%的敏感性,但特异性较低。100%的阴性预测值能够识别 患者。另一方面,在MiN组中,敏感性较低,这与大量假阴性结果有关。Anatomage Table可能是术前确定颈部淋巴结转移结外扩展的有用工具。

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