Ali H, Raslan N
Department of Pediatric Dentistry, Faculty of Dentistry, Tishreen University, Lattakia, Syria.
Eur Arch Paediatr Dent. 2021 Aug;22(4):633-642. doi: 10.1007/s40368-020-00600-3. Epub 2021 Feb 4.
This study aimed at the following: (a) To evaluate the effectiveness of direct pulp capping (DPC) in children's primary molars using a combination of three antibiotics (3Mix-MP) as direct pulp capping materials compared with Calcium Hydroxide and (b) to assess the impact of pulp exposure diameter, its location and restoration extent on the success rate of the technique.
This was a randomized double-blind, parallel, two-arm controlled trial. Forty-four primary molars with deep active caries, whose removal resulted in pulp exposures, were treated with direct pulp capping and were allocated randomly into two groups: Group A, DPC with 3Mix-MP; and group B, DPC with Calcium Hydroxide (CH). All teeth were restored with composite resin restorations. The exposures were classified according to their diameter, location and number of the filling surfaces. Clinical follow-ups were performed at intervals of 3 months for 1 year, and radiographical follow-ups were done after 6-12 months. Data were assessed using Chi-squared test (χ2) at a 0.05 level of significance and binary logistic regression was performed to determine the effect of the characteristics of the carious lesion on success rates.
The success rate of the technique was 54.5% in group A and 77.3% in group B, but the difference was not statistically significant. The pulp exposure diameter, its location and the number of the filling surfaces did not affect the success rate significantly.
(a) Direct pulp capping in primary teeth achieved comparable success rates with no significant difference between 3Mix-MP and Calcium hydroxide. (b) The exposure location, its diameter and the extent of the restoration had no significant impact on the success rates of direct pulp capping in primary teeth.
ISRCTN, ISRCTN13525994. Registered 31 October 2018 - Retrospectively registered, ( http:// www.isrctn.com/ISRCTN13525994 ).
本研究旨在：(a) 评估使用三种抗生素组合（3Mix-MP）作为直接盖髓材料与氢氧化钙相比，在儿童乳磨牙直接盖髓术（DPC）中的有效性；(b) 评估牙髓暴露直径、其位置和修复范围对该技术成功率的影响。
这是一项随机双盲、平行、双臂对照试验。44颗患有深龋且去龋后导致牙髓暴露的乳磨牙接受直接盖髓治疗，并随机分为两组：A组，使用3Mix-MP进行直接盖髓；B组，使用氢氧化钙（CH）进行直接盖髓。所有牙齿均用复合树脂修复。根据暴露的直径、位置和充填面数量进行分类。临床随访为期1年，每隔3个月进行一次，影像学随访在6至12个月后进行。使用卡方检验（χ2）在显著性水平0.05下评估数据，并进行二元逻辑回归以确定龋损特征对成功率的影响。
A组技术成功率为54.5%，B组为77.3%，但差异无统计学意义。牙髓暴露直径、其位置和充填面数量对成功率无显著影响。
(a) 乳牙直接盖髓术的成功率相当，3Mix-MP与氢氧化钙之间无显著差异。(b) 暴露位置、其直径和修复范围对乳牙直接盖髓术的成功率无显著影响。
ISRCTN，ISRCTN13525994。2018年10月31日注册 - 回顾性注册，（http://www.isrctn.com/ISRCTN13525994）
