Department of Pediatric and Preventive Dentistry, Government Dental College and Hospital, Nagpur, Maharashtra, India.
Department of Pediatric and Preventive Dentistry, Government Dental College and Hospital, Nagpur, Maharashtra, India, Phone: +91 9422277622, e-mail:
J Contemp Dent Pract. 2022 Feb 1;23(2):208-214.
The aim of this study was to evaluate clinical and radiographical success of ozonoid olive oil as an indirect pulp capping (IPC) agent in primary mandibular second molar when compared to calcium hydroxide and to evaluate the antimicrobial efficacy of ozonoid olive oil on and .
A split-mouth randomized controlled trial was conducted on 30 primary mandibular second molars in 15 children of age 5-9 years with deep dentinal carious lesion. Teeth were randomly allocated to two groups of 15 each. After achieving local anesthesia and rubber dam isolation, an IPC procedure was performed using ozonoid olive oil in group I and calcium hydroxide in group II. Teeth were evaluated clinically and radiographically at 6 and 12 months of follow-up for success or failure of IPC. The bacterial counts of and were measured before and after application of ozonoid olive oil for 60 seconds on dentinal tissue in group I and recorded as colony-forming units per mL (CFU/mL).
There were no statistically significant differences found between the materials used for IPC ( >0.05). About 93.33% and 100% clinical and radiographical success rates were seen in group I and group II, respectively. Statistically significant differences were observed for bacterial reduction after the application of ozonoid olive oil ( <0.05) for both the microorganisms.
The results of this study showed that the success of IPC is independent of capping material. Ozonoid olive oil, an antimicrobial agent, can also be used for IPC. The success of the IPC procedure depends on a reduction in the bacterial count and sealing of the tooth with hermetic restoration. More clinical studies with a larger sample size and longer follow-up duration are required for understanding the efficacy of this material.
Ozonoid olive oil can be used as an IPC agent in primary molars and also for a bacterial reduction in dentinal caries.
本研究旨在评估臭氧橄榄油作为间接盖髓剂（IPC）在儿童下颌第二恒磨牙时的临床和影像学成功率，并与氢氧化钙进行比较，同时评估臭氧橄榄油对 和 的抗菌效果。
对 15 名 5-9 岁儿童的 30 颗下颌第二恒磨牙进行了一项随机对照的分口临床试验，这些儿童的牙齿有深度牙本质龋损。将牙齿随机分为两组，每组 15 颗。在局部麻醉和橡皮障隔离后，在第 I 组中使用臭氧橄榄油，在第 II 组中使用氢氧化钙进行 IPC 处理。在 6 和 12 个月的随访中，对 IPC 的成功或失败进行临床和影像学评估。在第 I 组中，将臭氧橄榄油应用于牙本质组织 60 秒后，测量 和 的细菌计数，并以每毫升菌落形成单位（CFU/mL）记录。
两种用于 IPC 的材料之间没有统计学上的显著差异（ >0.05）。第 I 组和第 II 组的临床和影像学成功率分别为 93.33%和 100%。臭氧橄榄油应用后，两种微生物的细菌减少均有统计学显著差异（ <0.05）。
本研究结果表明，IPC 的成功与否与覆盖材料无关。臭氧橄榄油作为一种抗菌剂，也可用于 IPC。IPC 程序的成功取决于细菌数量的减少和用密封修复体密封牙齿。需要更多具有更大样本量和更长随访时间的临床研究来了解这种材料的疗效。
臭氧橄榄油可作为儿童乳磨牙的 IPC 制剂，也可减少牙本质龋中的细菌。
