Shanghai Institute of Traumatology and Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, Department of Orthopaedics, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China.
Adv Exp Med Biol. 2021;1295:163-190. doi: 10.1007/978-3-030-58174-9_8.
Lately, a remarkable progress has been recorded in the field of electrospinning for the preparation of numerous types of nanofiber scaffolds. These scaffolds present some remarkable features including high loading capacity and encapsulation efficiency, superficial area and porosity, potential for modification, structure for the co-delivery of various therapies, and cost-effectiveness. Their present and future applications for cancer diagnosis and treatment are promising and pioneering. In this chapter we provide a comprehensive overview of electrospun nanofibers (ESNFs) applications in cancer diagnosis and treatment, covering diverse types of drug-loaded electrospun nanofibers.
最近，在制备各种类型的纳米纤维支架的静电纺丝领域取得了显著的进展。这些支架具有一些显著的特点，包括高载药量和包封效率、比表面积和孔隙率、修饰的潜力、各种治疗方法的共同传递结构以及成本效益。它们在癌症诊断和治疗中的应用具有广阔的前景和开拓性。在本章中，我们全面概述了电纺纳米纤维（ESNFs）在癌症诊断和治疗中的应用，涵盖了各种类型的载药电纺纳米纤维。
Adv Exp Med Biol. 2021
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