A-10, Radhey Kunj Apartment, Shahi Baugh, Ahmedabad, 380004, India.
National Institute of Occupational Health (ICMR), Ahmedabad, 380016, India.
Rev Environ Health. 2021 Feb 3;36(4):565-575. doi: 10.1515/reveh-2020-0136. Print 2021 Dec 20.
Excessive air pollution, both ambient and indoor are might be detrimental to human wellbeing and are related to morbidity and mortality, it may also affect the reproductive function and its outcome. It is a recognized fact that air pollution contains several toxicants, gases, particulate matter, toxic metals etc. Some of them might affect reproductive and developmental process and a few are persistent. The information accessible on air pollution to human male reproduction is stated to affect semen quality by diminishing one or more sperm quality parameters i.e., sperm morphology, concentration, motility etc. and may causes sperm DNA damage, these might alter the fertility potential which in turn affect pregnancy or its outcome. The impact might be related to the pollutant's concentration and duration of exposure. The data on impact of air contamination on endocrine function are inadequate, inconsistence and the diversity of existence of air contaminants in area to area and multiplicity in semen quality parameters assessed in various studies as well as study design variables complicated the problem of evaluation of impact of air pollution on male reproduction. The data available suggests the air pollution is might be injurious to human male reproductive health, which depends upon amounts of air pollutants in the air, duration of exposure etc. but more comprehensive data are needed to substantiate the findings. The data are also needed on indoor air pollution on reproduction as people are might be subjected to greater quantities of some of the indoor air pollutants as compared to ambient air pollution.
过度的空气污染，无论是环境中的还是室内的，都可能对人类健康有害，并与发病率和死亡率有关，也可能影响生殖功能及其结果。众所周知，空气污染中含有几种有毒物质、气体、颗粒物、有毒金属等。其中一些可能会影响生殖和发育过程，而其中一些是持久性的。关于空气污染对人类男性生殖的信息表明，通过减少一个或多个精子质量参数，如精子形态、浓度、活力等，会影响精液质量，并可能导致精子 DNA 损伤，这可能会改变生育能力，从而影响怀孕或其结果。这种影响可能与污染物的浓度和暴露时间有关。关于空气污染对内分泌功能影响的数据不足、不一致，以及空气污染物在不同地区的存在多样性和在不同研究中评估的精液质量参数的多样性以及研究设计变量使评估空气污染对男性生殖的影响的问题变得复杂。现有数据表明，空气污染可能对人类男性生殖健康有害，这取决于空气中的污染物数量、暴露时间等，但需要更全面的数据来证实这一发现。也需要关于室内空气污染对生殖的影响的数据，因为与环境空气污染相比，人们可能会接触到更多的一些室内空气污染物。
