免疫功能正常患者的眼部合并感染和 - 病例报告。

Ocular Co-infection with and in an Immunocompetent Patient - A Case Report.

机构信息

Uveitis & Cornea Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

Uveitis Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

出版信息

Ocul Immunol Inflamm. 2022 May 19;30(4):1022-1026. doi: 10.1080/09273948.2020.1849738. Epub 2021 Feb 5.

DOI:10.1080/09273948.2020.1849738

PMID:33544637

Abstract

PURPOSE

To report a case of ocular co-infection with and in an immunocompetent woman.

METHOD

Retrospective observational case report.

RESULT

A 61-year-old woman presented with decreased vision and floaters in the right eye of 1-month duration. Ocular examination revealed panuveitis with a large yellowish-white retinochoroiditis lesion adjacent to a chorioretinal scar. Investigations showed positive Mantoux test, QuantiFERON TB test, and HRCT chest suggestive of active pulmonary tuberculosis. Serology revealed raised IgG anti antibody. Vitreous aspirate was positive for and genome by polymerase chain reaction and showed high IgG and IgM antibodies. She was treated with anti toxoplasmic and antitubercular therapy along with oral corticosteroid and therapeutic vitrectomy.

CONCLUSION

Ocular tuberculosis and toxoplasmosis can not only mimic each other but also present as co-infection in rare cases.

摘要

目的

报告一例免疫功能正常的女性眼内合并感染弓形虫和结核分枝杆菌的病例。

方法

回顾性观察性病例报告。

结果

一名 61 岁女性因右眼视力下降和眼前漂浮物就诊，病程 1 个月。眼部检查显示全葡萄膜炎，伴有紧邻脉络膜瘢痕的大的黄白色视网膜脉络膜炎病变。检查显示结核菌素纯蛋白衍生物试验和结核菌素干扰素释放试验阳性，胸部高分辨率计算机断层扫描提示活动性肺结核。血清学检查显示 IgG 抗弓形虫抗体升高。玻璃体抽吸物通过聚合酶链反应检测出弓形虫和结核分枝杆菌基因组，并显示 IgG 和 IgM 弓形虫抗体升高。她接受了抗弓形虫和抗结核治疗以及口服皮质类固醇和玻璃体切除术治疗。