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在埃塞俄比亚,孕妇开始产前护理的时间及其预测因素:Cox-gamma 共享脆弱模型。

Time to initiation of antenatal care and its predictors among pregnant women in Ethiopia: Cox-gamma shared frailty model.

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

Department of Reproductive and Family Health, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

出版信息

PLoS One. 2021 Feb 5;16(2):e0246349. doi: 10.1371/journal.pone.0246349. eCollection 2021.

Abstract

BACKGROUND

Timely initiating antenatal care (ANC) is crucial in the countries that have high maternal morbidity and mortality. However, in developing countries including Ethiopia, pregnant mother's time to initiate antenatal care was not well-studied. Therefore, this study aimed to assess time to first ANC and its predictors among pregnant women in Ethiopia.

METHODS

A community-based cross-sectional study was conducted among 7,543 pregnant women in Ethiopia using the Ethiopian Demographic Health Survey (EDHS), 2016 data. A two-stage stratified cluster sampling was employed. The Kaplan-Meier (KM) method was used to estimate time to first antenatal care visit. Cox-gamma shared frailty model was applied to determine predictors. Adjusted Hazard Ratio (AHR) with 95% confidence interval was reported as the effect size. Model adequacy was assessed by using the Cox-Snell residual plot. Statistical significance was considered at p value <0.05. For data management and analysis Stata 14 was used.

RESULTS

The median time to first ANC was 5 months with IQR (3,-). The independent predictors of time to first ANC visit were primary education [AHR: 1.24 (95%CI, 1.13-1.35)], secondary education [AHR: 1.28(95% CI, 1.11-1.47)], higher education [AHR: 1.43 (1.19-1.72)] as compared to women with no formal education. Having media exposure [AHR: 1.13 (95% CI, 1.03-1.24)], early initiation of ANC increases by 25% [AHR: 1.25 (95% CI, 1.12-1.40)] in poorer, 32% [AHR: 1.32 (95% CI, 1.17-1.49)] in middle, 37% [AHR: 1.37 (95% CI, 1.20-1.56)] in richer and 41% [AHR: 1.41 (95%CI, 1.1.19-1.67)] in richest households as compared to poorest household wealth index. Living in city administration, media exposure and community women literacy were also enabler factors, while, long distance from health facility and nomadic region residency were hindering factors of early ANC visit.

CONCLUSIONS

The current study revealed that women's time to first antenatal care visit was by far late in Ethiopia as compared to the world health organization recommendation (WHO). The predictors of time to first ANC visit were education status of women, having media exposure, level of household wealth index, community women literacy ad distance to health facility. It is vital that maternal and child health policies and strategies better to be directed at women development and also designing and applying interventions that intended to increase timely initiation ANC among pregnant-women. Researchers also recommended conducting studies using a stronger design like a cohort to establish temporality and reduce biases.

摘要

背景

在孕产妇发病率和死亡率较高的国家,及时开展产前保健(ANC)至关重要。然而,在包括埃塞俄比亚在内的发展中国家,孕妇开始产前保健的时间并没有得到很好的研究。因此,本研究旨在评估埃塞俄比亚孕妇首次产前保健就诊的时间及其预测因素。

方法

本研究采用埃塞俄比亚 2016 年人口与健康调查(EDHS)的数据,对 7543 名孕妇进行了一项基于社区的横断面研究。采用两阶段分层聚类抽样。使用 Kaplan-Meier(KM)方法估计首次产前保健就诊时间。应用 Cox-gamma 共享脆弱性模型确定预测因素。报告调整后的危害比(AHR)及其 95%置信区间作为效应量。通过 Cox-Snell 残差图评估模型充分性。p 值<0.05 表示具有统计学意义。数据管理和分析采用 Stata 14 软件。

结果

首次 ANC 就诊的中位数时间为 5 个月,IQR(3,-)。首次 ANC 就诊时间的独立预测因素包括小学教育[AHR:1.24(95%CI,1.13-1.35)],中学教育[AHR:1.28(95%CI,1.11-1.47)],高等教育[AHR:1.43(1.19-1.72)]与未接受正规教育的女性相比。有媒体接触[AHR:1.13(95%CI,1.03-1.24)],早期开始 ANC 增加 25%[AHR:1.25(95%CI,1.12-1.40)],在较贫穷家庭中增加 32%[AHR:1.32(95%CI,1.17-1.49)],在中等家庭中增加 37%[AHR:1.37(95%CI,1.20-1.56)],在较富裕家庭中增加 41%[AHR:1.41(95%CI,1.1.19-1.67)],与最贫困家庭财富指数相比。居住在城市行政区域、媒体接触和社区妇女识字率也是促进因素,而距离保健设施较远和游牧地区居住是早期 ANC 就诊的阻碍因素。

结论

目前的研究表明,与世界卫生组织(WHO)的建议相比,埃塞俄比亚妇女首次产前保健就诊的时间非常晚。首次 ANC 就诊时间的预测因素是妇女的教育状况、媒体接触、家庭财富指数水平、社区妇女识字率以及与保健设施的距离。重要的是,母婴健康政策和战略应更好地针对妇女发展,并设计和应用旨在增加孕妇及时开始 ANC 的干预措施。研究人员还建议使用更强的设计(如队列研究)进行研究,以确定时间顺序并减少偏倚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e13f/7864666/42ae6e2bccd6/pone.0246349.g001.jpg

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