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冠状病毒(SARS-CoV-2):潜在疫苗的系统评价。

Coronavirus (SARS-CoV-2): a systematic review for potential vaccines.

机构信息

Division of Virology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.

Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.

出版信息

Hum Vaccin Immunother. 2022 Dec 31;18(1):1865774. doi: 10.1080/21645515.2020.1865774. Epub 2021 Feb 5.

Abstract

COVID-19 is an international public health emergency in need of effective and safe vaccines for SARS-CoV-2. A systematic review has been done to analyze the availability, development and status of new COVID-19 vaccine candidates as well as the status of vaccines for other diseases that might be effective against SARS-CoV-2 infection. PubMed, MEDLINE, EMBASE, Science Direct, Google Scholar, Cochrane library, ClinicalTrials.gov, Web of Science and different trial registries were searched for currently available and probable future vaccines. Articles and ongoing clinical trials are included to ascertain the availability and developmental approaches of new vaccines that could limit the present and future outbreaks. Pharmaceutical companies and institutions are at different stages of developing new vaccines, and extensive studies and clinical trials are still required.

摘要

COVID-19 是一项国际公共卫生紧急事件,需要针对 SARS-CoV-2 开发有效且安全的疫苗。系统评价旨在分析新型 COVID-19 候选疫苗的可及性、开发状况和研究进展,以及针对可能对 SARS-CoV-2 感染有效的其他疾病的疫苗的状况。检索了 PubMed、MEDLINE、EMBASE、Science Direct、Google Scholar、Cochrane 图书馆、ClinicalTrials.gov、Web of Science 和不同的试验注册处,以确定目前可及的和可能的未来疫苗。纳入了文章和正在进行的临床试验,以确定新疫苗的可及性和研发方法,这些疫苗可能会限制当前和未来的疫情爆发。制药公司和机构处于开发新型疫苗的不同阶段,仍需要进行广泛的研究和临床试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f75b/8920137/1012a99c7dd6/KHVI_A_1865774_F0001_OC.jpg

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