Department of Rehabilitation Sciences, Faculty of Education, East China Normal University, Shanghai.
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province.
Medicine (Baltimore). 2021 Jan 22;100(3):e23847. doi: 10.1097/MD.0000000000023847.
Sudden hearing loss (SHL) is a disease, at the same time a symptom, which needs to be treated in a timely manner and counts as an emergency health problem in the Department of Otolaryngology. There are many types of sudden hearing loss and among them, the occurrence of all-frequency descending sudden hearing loss and high frequency sudden hearing loss are high. The conventional treatment for these 2 types of sudden hearing loss sometimes is not as effective as expected. Postauricular injection of glucocorticoids could be the most effective treatment method. However, the effectiveness and safety of postauricular injection of glucocorticoid needs to be assessed systematically.
The protocol for the meta-analysis was conducted under the guidance of Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). The aim is to undertake a systematic review and meta-analysis on the effectiveness and safety of postauricular injection of glucocorticoid to treat patient diagnosed with all-frequency and high frequency descending sudden hearing loss. We searched through the following databases: English databases (PubMed, EMBASE, Web of Science) and Chinese databases (CNKI, Wanfang databases, CBM, VIP). The final selected articles will be evaluated using Cochrane RCT evaluation criteria. Revman 5.0 will be used for data analysis. Subgroup analysis, sensitivity analysis, and meta regression will detect sources of heterogeneity. Ethics approval was not required for this protocol. The findings will be disseminated through journal articles or conference presentations.
DOI 10.17605/OSF.IO/5Q9NA.
Objectively, evaluate the efficacy and safety of postauricular injection of glucocorticoid in treating all-frequency descending sudden hearing loss and high frequency sudden hearing loss.
To provide evidence-based medicine for glucocorticoid treatment methods in patients with all-frequency descending sudden hearing loss and high frequency descending hearing loss.
突发性听力损失（SHL）既是一种疾病，也是一种症状，需要及时治疗，在耳鼻喉科被视为紧急健康问题。突发性听力损失有多种类型，其中全频下降型突发性听力损失和高频突发性听力损失较为常见。对于这两种类型的突发性听力损失，常规治疗有时并不如预期有效。耳后注射糖皮质激素可能是最有效的治疗方法。然而，耳后注射糖皮质激素的有效性和安全性需要系统评估。
本荟萃分析方案是在系统评价和荟萃分析报告的首选条目（PRISMA-P）的指导下制定的。目的是对耳后注射糖皮质激素治疗全频下降型和高频下降型突发性听力损失患者的有效性和安全性进行系统评价和荟萃分析。我们检索了以下数据库：英文数据库（PubMed、EMBASE、Web of Science）和中文数据库（CNKI、万方数据库、CBM、VIP）。最终选择的文章将根据 Cochrane RCT 评价标准进行评估。Revman 5.0 将用于数据分析。亚组分析、敏感性分析和荟萃回归将用于检测异质性来源。本方案不需要伦理批准。研究结果将通过期刊文章或会议报告进行发表。
OSF 注册号：DOI 10.17605/OSF.IO/5Q9NA。
客观评估耳后注射糖皮质激素治疗全频下降型突发性听力损失和高频突发性听力损失的疗效和安全性。
为全频下降型突发性听力损失和高频下降型突发性听力损失患者的糖皮质激素治疗方法提供循证医学依据。
