Hospital of Chengdu University of Traditional Chinese Medicine.
Chengdu University of Traditional Chinese Medicine.
Medicine (Baltimore). 2021 Jan 22;100(3):e23918. doi: 10.1097/MD.0000000000023918.
Obesity is an independent risk factor for the occurrence and development of diabetes. Patients with diabetes combined with obesity will face serious burdens such as increase in insulin resistance and difficulty in blood glucose control. As a safe, effective, economical, and simple intervention, Tuina is more acceptable to the public than drugs. The objective of this systematic evaluation and meta-analysis is to evaluate the efficacy and safety of Tuina for diabetes with obesity.
We will search the following electronic databases: PubMed, Embase, Cochrane Library, Web of science, Chinese National Knowledge Infrastructure (CNKI), Sino Med, Wanfang, Chinese Clinical Trial Registry System, China Biomedical Literature Database (CBM). The time limit for retrieving studies is from establishment to November 2020 for each database. Randomized controlled clinical trials related to Tuina intervention on diabetes with obesity will be included. Data synthesis, sensitivity analysis, subgroup analysis as well as the assessment of bias risk will be conducted by using Stata V.13.0 and Review manager 5.3 software.
This study will provide a quantitative and standardized evaluation for the efficacy of Tuina therapy on diabetes with obesity.
This systematic review and meta-analysis will provide the high-quality evidence of whether Tuina is an effective intervention for diabetes with obesity.
INPLASY2020110106.
肥胖是糖尿病发生和发展的独立危险因素。糖尿病合并肥胖的患者将面临胰岛素抵抗增加和血糖控制困难等严重负担。推拿作为一种安全、有效、经济、简便的干预措施，比药物更能被公众接受。本系统评价和荟萃分析的目的是评估推拿治疗肥胖型糖尿病的疗效和安全性。
我们将检索以下电子数据库：PubMed、Embase、 Cochrane Library、Web of science、中国知网（CNKI）、中国生物医学文献数据库（CBM）。每个数据库的检索时间限制为从建立到 2020 年 11 月。将纳入推拿干预肥胖型糖尿病的随机对照临床试验。采用 Stata V.13.0 和 Review Manager 5.3 软件进行数据合并、敏感性分析、亚组分析和偏倚风险评估。
本研究将对推拿疗法治疗肥胖型糖尿病的疗效进行定量和标准化评价。
本系统评价和荟萃分析将为推拿是否是肥胖型糖尿病的有效干预措施提供高质量证据。
INPLASY2020110106。
