调节性 T 细胞对肝细胞癌预后影响的系统评价和荟萃分析方案。
Impact of regulatory T cells on the prognosis of hepatocellular carcinoma: A protocol for systematic review and meta analysis.
机构信息
Department of Medical Laboratory, Yancheng No.1 People's Hospital & Yancheng First Hospital Affiliated Hospital of Nanjing University Medical School.
College of Medical Technology, Jiangsu Vocational College of Medicine, Yancheng, P.R. China.
出版信息
Medicine (Baltimore). 2021 Jan 22;100(3):e23957. doi: 10.1097/MD.0000000000023957.
BACKGROUND
This meta-analysis aimed to systematically review current available literature to assess the impact of regulatory T cells (Tregs) on the prognosis of hepatocellular carcinoma (HCC).
METHODS
We will browse the online databases of PubMed and Cochrane Library. The summary hazard ratio (HR) and their 95% confidence intervals (CIs) will be combined to present the value reported in the study.
CONCLUSION
Our meta-analysis will provide useful guidance in treatment of HCC based on the reported evidences regarding the impact of Tregs on the prognosis of HCC.
OSF REGISTRATION NUMBER
10.17605/OSF.IO/3Q8PW.
背景
本荟萃分析旨在系统地回顾现有文献，评估调节性 T 细胞（Tregs）对肝细胞癌（HCC）预后的影响。
方法
我们将检索 PubMed 和 Cochrane Library 的在线数据库。将汇总的风险比（HR）及其 95%置信区间（CI）合并，以呈现研究报告中的数值。
结论
我们的荟萃分析将基于 Tregs 对 HCC 预后影响的报告证据，为 HCC 的治疗提供有用的指导。
OSF 注册号：10.17605/OSF.IO/3Q8PW。
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