General Paediatrics, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK
General Paediatrics, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.
BMJ Case Rep. 2021 Feb 5;14(2):e240532. doi: 10.1136/bcr-2020-240532.
We describe a rare case of a 4-month-old girl presenting with a several month history of reduced movement to the left arm accompanied by a maculopapular rash to the limbs. X-ray findings included inflammatory periosteal changes to the radius and ulna. IgM was detected in both baby and mother, and a diagnosis of congenital syphilis was made. This case is an interesting clinical picture with a variety of important differential diagnoses, including non-accidental injury, malignancy, autoimmune disease and other congenital infections. With an increasing rate of congenital syphilis infection in the developed world, it is vital that clinicians are able to recognise symptoms to ensure prompt diagnosis and treatment. In this respect, we can attempt to avoid the chronic and potentially life-threatening complications of untreated infection.
我们描述了一例罕见病例,一名 4 个月大的女孩,左侧手臂活动减少数月,并伴有四肢斑丘疹。X 射线检查结果包括桡骨和尺骨的炎症性骨膜变化。婴儿和母亲的 IgM 均被检测到,诊断为先天性梅毒。这种情况是一种有趣的临床表现,有多种重要的鉴别诊断,包括非意外伤害、恶性肿瘤、自身免疫性疾病和其他先天性感染。随着发达国家先天性梅毒感染率的增加,临床医生能够识别症状以确保及时诊断和治疗至关重要。在这方面,我们可以尝试避免未经治疗的感染带来的慢性和潜在危及生命的并发症。