Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Faculty of Life Sciences and Medicine, King's College London, London, UK.
Eur Eat Disord Rev. 2021 May;29(3):371-392. doi: 10.1002/erv.2820. Epub 2021 Feb 6.
Evidence regarding global trends in length of stay for patients with anorexia nervosa is limited. The aim of this study is to conduct a meta-analysis examining the length of stay for anorexia nervosa patients globally, and to investigate moderators of the variance.
Medline, EMBASE and PsycINFO were searched for studies published up to January 2019. Two independent reviewers assessed the eligibility of each report based on predefined inclusion criteria. A meta-analysis was performed to calculate a pooled mean length of stay using the random-effects model. Subgroup analyses and meta-regression were conducted to explore potential sources of heterogeneity between studies.
Of 305 abstracts reviewed, 71 studies met the inclusion criteria, generating 111 datasets. The pooled mean length of stay (95% confidence interval) was 76.3 days (73.3, 79.4) using the random-effects model, with marked variation across countries and time. Heterogeneity between studies was explained by age and admission body mass index.
This meta-analysis found that although clinical features do contribute to length of admissions for anorexia nervosa, there are also global and temporal variations. Future research should provide an in-depth analysis of why and how this variation exists and what the impact is on the well-being of people with anorexia nervosa.
关于厌食症患者住院时间全球趋势的证据有限。本研究旨在进行荟萃分析，以检查全球范围内厌食症患者的住院时间，并探讨变异性的调节因素。
检索了 Medline、EMBASE 和 PsycINFO 中截至 2019 年 1 月发表的研究。两名独立的审查员根据预先设定的纳入标准评估了每份报告的资格。使用随机效应模型进行荟萃分析以计算汇总的平均住院时间。进行亚组分析和荟萃回归分析以探讨研究之间异质性的潜在来源。
在审查的 305 篇摘要中，有 71 项研究符合纳入标准，产生了 111 个数据集。使用随机效应模型，汇总的平均住院时间（95%置信区间）为 76.3 天（73.3，79.4），各国和时间之间存在明显差异。研究之间的异质性由年龄和入院时的体重指数解释。
这项荟萃分析发现，尽管临床特征确实有助于厌食症的住院时间，但也存在全球和时间上的变化。未来的研究应深入分析这种变化存在的原因和方式，以及对厌食症患者的幸福感的影响。
