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两种中胚层疗法方案治疗警犬背部疼痛的比较:一项回顾性研究。

Comparison of Two Mesotherapy Protocols in the Management of Back Pain in Police Working Dogs: A Retrospective Study.

机构信息

MED - Mediterranean Institute for Agriculture, Environment and Development, Instituto de Investigação e Formação Avançada, Universidade de Évora, Pólo da Mitra, Ap. 94, 7006-554; Divisão de Medicina Veterinária, Guarda Nacional Republicana, Lisbon, Portugal.

Divisão de Medicina Veterinária, Guarda Nacional Republicana, Lisbon, Portugal.

出版信息

Top Companion Anim Med. 2021 Jun;43:100519. doi: 10.1016/j.tcam.2021.100519. Epub 2021 Feb 4.

DOI:10.1016/j.tcam.2021.100519
PMID:33548549
Abstract

This study aimed to compare 2 protocols for the management of back pain in police working dogs. Twenty animals were signaled based on history, trainer complaints, physical and radiographic examination consistent with back pain. In a retrospective study, 2 groups were considered: GM, treated with a solution comprising a combination of lidocaine, dexamethasone, and tiocolchicoseide; and GT, treated with the same solution, with the addition of Traumeel LT. Response to treatment, measured by the Canine Brief Pain Inventory (CBPI, divided into pain interference score - PIS, and pain severity score - PSS) and Hudson Visual Analogue Scale (HVAS), was evaluated before treatment (T0), after 15 (+15d) days and 1 (+30d), 2 (+60d), 3 (+90d), 4 (+120d), 5 (+150d) and 6 (+180d) months. Results were compared using an independent samples t-test or a Paired Samples t-test. Comparing results for each moment with T0 within each group, differences where observed only in GM at +15d (P < .01 for PIS and P < .01 for PSS), +30d (P = .04 for PIS and P < .01 for PSS), +60d (P = .03 for PIS and P = .02 for PSS) and +90d (P = .02 for PSS). Treatment was successful in reducing PSS (reduction of ≥1) in 8/10 animals of GM at +15d (80%), 8/10 at +30d (80%), 5/10 at +60d (50%), 4/10 at +90d (40%), 3/9 at +120d (33.3%) and 2/9 at +150d -+ 180d (22.2%). In GT, treatment was successful in 1/10 at +15d -+30d (10%), 2/10 at +60d (20%) and 1/10 at +90d (10%). No differences were observed with HVAS any time point for either intervention or when comparing groups in each moment. The protocol used in GM produced significant improvements, while the addition of Traumeel did not, rather reducing the effect of treatment in working dogs with back pain. Further studies are required.

摘要

本研究旨在比较两种方案治疗警犬背部疼痛的效果。二十只动物根据病史、训练员投诉、与背部疼痛一致的物理和放射学检查进行标记。在一项回顾性研究中,考虑了两组:GM 组,用包含利多卡因、地塞米松和硫代秋水仙碱的混合溶液治疗;GT 组,用相同的溶液治疗,另外加入 Traumeel LT。用犬简明疼痛量表(CBPI,分为疼痛干扰评分 - PIS 和疼痛严重程度评分 - PSS)和 Hudson 视觉模拟量表(HVAS)测量治疗前后(T0)、治疗后 15 天(+15d)、1 个月(+30d)、2 个月(+60d)、3 个月(+90d)、4 个月(+120d)、5 个月(+150d)和 6 个月(+180d)的反应。使用独立样本 t 检验或配对样本 t 检验比较结果。比较每组每个时间点与 T0 的结果,仅在 GM 组中观察到以下差异:+15d(P <.01 时 PIS 和 P <.01 时 PSS)、+30d(P =.04 时 PIS 和 P <.01 时 PSS)、+60d(P =.03 时 PIS 和 P =.02 时 PSS)和+90d(P =.02 时 PSS)。GM 组在+15d 时 8/10 只动物(80%)、+30d 时 8/10 只动物(80%)、+60d 时 5/10 只动物(50%)、+90d 时 4/10 只动物(40%)、+120d 时 3/9 只动物(33.3%)和+150d-+180d 时 2/9 只动物(22.2%)成功降低 PSS(降低≥1)。在 GT 组中,+15d-+30d 时有 1/10 只动物(10%)、+60d 时有 2/10 只动物(20%)和+90d 时有 1/10 只动物(10%)成功治疗。两种干预措施在任何时间点或在每组比较时,HVAS 均无差异。GM 组使用的方案显著改善了疼痛,而添加 Traumeel 并没有改善,反而降低了患有背部疼痛的工作犬的治疗效果。需要进一步研究。

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