Guarda Nacional Republicana (Portuguese Gendarmerie), Lisbon, Portugal (Alves, Santos, Jorge); MED - Mediterranean Institute for Agriculture, Environment and Development, Instituto de Investigação e Formação Avançada, Universidade de Évora, Pólo da Mitra, Ap. 94, 7006-554 Évora, Portugal (Alves); UNIR-Universidad Internacional de La Rioja, Logroño, Spain (Lafuente).
Can Vet J. 2022 Jun;63(6):597-602.
The aim of this study was to document the effects of mesotherapy in working dogs diagnosed with hip osteoarthritis (OA) and related pain. Ten police working dogs with hip OA and related pain were treated with a combination of lidocaine, piroxicam, and thiocolchicoside, injected in multiple intradermal points. Seven treatment sessions were conducted. The Canine Brief Pain Inventory (CBPI) and the Hudson Visual Analogue Scale (HVAS) were used in the assessment of response to treatment compared to evaluation before treatment (T0), after 15 d, 30 d, 60 d, 90 d, 120 d, 150 d, and 180 d after initial treatment. Results were compared using the Wilcoxon signed-rank test. Significant differences were experienced in CBPI scores comparing moments with T0: at 15 d ( = 0.03 for Pain Interference Score - PIS) and = 0.02 for Pain Severity Score - PSS), 30 d ( < 0.05 for PIS and < 0.05 for PSS), 60 d ( = 0.04 for PIS and = 0.01 for PSS) and 180 d ( = 0.04 for PSS). Individual treatment results were considered successful in 40% of animals at 15 d and 30 d, 66.7% at 60 d, 44% at 90 d, 37.5% at 120 d, and 25% at 150 d. The HVAS scores showed no significant differences. Mesotherapy may be an option for the treatment of canine musculoskeletal-related pain. Further studies are required.
本研究旨在记录皮内多点注射治疗犬髋关节骨关节炎（OA）及相关疼痛的效果。10 只髋关节 OA 及相关疼痛的警犬接受了利多卡因、吡罗昔康和硫代秋水仙碱联合治疗。共进行了 7 次治疗。使用犬简短疼痛量表（CBPI）和哈德逊视觉模拟量表（HVAS）评估治疗反应，与治疗前（T0）、治疗后 15d、30d、60d、90d、120d、150d 和 180d 进行比较。采用 Wilcoxon 符号秩检验比较结果。与 T0 相比，CBPI 评分在以下时刻有显著差异：15d（疼痛干扰评分 PIS： = 0.03）和 30d（PIS： < 0.05，PSS： < 0.05）、60d（PIS： = 0.04，PSS： < 0.05）和 180d（PSS： = 0.04）。在 15d 和 30d 时，40%的动物个体治疗结果被认为是成功的，60d 时为 66.7%，90d 时为 44%，120d 时为 37.5%，150d 时为 25%。HVAS 评分无显著差异。皮内多点注射治疗可能是治疗犬肌肉骨骼相关疼痛的一种选择。需要进一步研究。
