Division of Pediatric Endocrinology, McMaster Children's Hospital, Hamilton, Ontario, Canada.
Division of Pediatric Endocrinology, McMaster Children's Hospital, Hamilton, Ontario, Canada.
Can J Diabetes. 2021 Aug;45(6):571-574. doi: 10.1016/j.jcjd.2020.11.007. Epub 2020 Nov 26.
Insulin edema is a rare and poorly understood complication of insulin therapy. It has been associated with the initiation of insulin in patients with newly diagnosed diabetes or the intensification of insulin therapy in those with poor glycemic control. This condition is rarely reported in pediatric patients. We describe a case of insulin edema in a 14-year-old boy with potential risk factors of highly elevated glycated hemoglobin at diagnosis and history of unilateral renal atrophy. We also present a discussion of the pathophysiology of this condition and a review of the pediatric literature.
胰岛素水肿是胰岛素治疗罕见且尚未完全阐明的并发症。它与新诊断糖尿病患者开始使用胰岛素或血糖控制不佳的患者强化胰岛素治疗有关。这种情况在儿科患者中很少见。我们描述了一例 14 岁男孩的胰岛素水肿病例，该男孩存在高糖化血红蛋白诊断时和单侧肾萎缩的潜在危险因素。我们还讨论了这种情况的病理生理学，并回顾了儿科文献。
