Department of Vascular Surgery, Milwaukee Veterans Affairs Medical Center, Milwaukee, WI; Division of Vascular and Endovascular Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.
Department of Plastic Surgery, Milwaukee Veterans Affairs Medical Center, Milwaukee, WI; Department of Plastic Surgery, Medical College of Wisconsin, Milwaukee, WI.
Ann Vasc Surg. 2021 Jul;74:518.e13-518.e23. doi: 10.1016/j.avsg.2020.12.046. Epub 2021 Feb 4.
Primary aortoduodenal fistula is a rare, life-threatening pathology that is difficult to diagnose and manage. We present the case of a 64-year-old male with a primary aortoduodenal fistula. Our patient initially underwent an endovascular aneurysm repair at an outside institution before being transferred to our tertiary care center, where he ultimately had definitive management with an extra-anatomic bypass, aortic ligation, duodenal resection with primary anastomosis, and gastrojejunostomy tube placement. His surgical cultures grew Candida albicans, and he was discharged with a 6-week course of intravenous antibiotics with subsequent antibiotic suppression for 1 year. He died 14 months postoperatively from tongue squamous cell carcinoma. We also review the current literature regarding epidemiology, pathology, diagnostics, management, and case reports from 2015 to present. Overall, timely diagnosis and treatment is imperative for reducing mortality from primary aortoduodenal fistula, and although formal consensus is lacking regarding most clinical aspects, an increasing number of case reports has helped describe options for management.
原发性主动脉-十二指肠瘘是一种罕见的、危及生命的疾病,其诊断和治疗都极具难度。我们报告了一例 64 岁男性原发性主动脉-十二指肠瘘患者的病例。该患者最初在外院接受了血管内动脉瘤修复术,然后转至我们的三级医疗中心,最终通过体外旁路、主动脉结扎、十二指肠切除和一期吻合术以及胃空肠造口管放置进行了确定性治疗。他的外科培养物中生长出白色念珠菌,出院后接受了 6 周的静脉抗生素治疗,随后进行了 1 年的抗生素抑制治疗。术后 14 个月,他因舌鳞状细胞癌去世。我们还回顾了 2015 年至今关于该病的流行病学、病理学、诊断、治疗和病例报告的现有文献。总体而言,及时诊断和治疗对于降低原发性主动脉-十二指肠瘘的死亡率至关重要,尽管大多数临床方面尚未达成正式共识,但越来越多的病例报告有助于描述管理选择。