Jung Ji Eun, Oh Seyeol, Kwon In Gyu
Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Yonsei Med J. 2025 Jan;66(1):37-42. doi: 10.3349/ymj.2023.0552.
This study aimed to analyze the characteristics and outcomes of patients with an aortoduodenal fistula (ADF) who underwent surgical treatment at a single institution.
The data of patients diagnosed with ADF at the Yonsei University Gangnam Severance Hospital, South Korea, between 2019 and 2022 were included. Primary repair and segmental resection of the duodenum with duodeno-jejunostomy were the two main methods used to repair ADF.
Among the 15 patients analyzed, most were male, and the median age was 68 years. Based on the cause of ADF, five patients had primary ADF, whereas the remaining had secondary ADF. The average duration from fistula diagnosis to surgery was 23.5 days (2.8 days in primary ADF cases and 33.8 days in secondary ADF cases). Primary repair of the ADF was performed for eight patients, and segmental resection of the duodenum with duodeno-jejunostomy was performed for the remaining patients. Omentopexy was performed for all patients. The median duration of hospital stay was 32.7 days. Three patients died after surgery; however, all 11 patients operated on by the single experienced surgeon survived until the last follow-up.
To the best of our knowledge, this study is the first original article on ADF. Our findings suggest that ADF repairs performed by experienced surgeons would provide favorable results. Although primary repair is the first treatment choice, duodeno-jejunostomy is recommended when it is not feasible. By choosing the appropriate procedure depending on the case, favorable outcomes without any fatalities can be achieved.
本研究旨在分析在单一机构接受手术治疗的主动脉十二指肠瘘(ADF)患者的特征和治疗结果。
纳入2019年至2022年期间在韩国延世大学江南 Severance 医院被诊断为ADF的患者数据。ADF修复的两种主要方法是十二指肠一期修复和十二指肠节段切除并十二指肠空肠吻合术。
在分析的15例患者中,大多数为男性,中位年龄为68岁。根据ADF的病因,5例患者为原发性ADF,其余为继发性ADF。从瘘管诊断到手术的平均时间为23.5天(原发性ADF病例为2.8天,继发性ADF病例为33.8天)。8例患者进行了ADF一期修复,其余患者进行了十二指肠节段切除并十二指肠空肠吻合术。所有患者均进行了网膜固定术。中位住院时间为32.7天。3例患者术后死亡;然而,由这位经验丰富的单一外科医生进行手术的11例患者均存活至最后一次随访。
据我们所知,本研究是关于ADF的第一篇原创文章。我们的研究结果表明,由经验丰富的外科医生进行ADF修复可取得良好效果。虽然一期修复是首选治疗方法,但在不可行时建议进行十二指肠空肠吻合术。根据具体情况选择合适的手术方法,可以实现良好的治疗效果且无死亡病例。