LEPABE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal.
LEPABE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal.
Drug Discov Today. 2021 Jun;26(6):1340-1346. doi: 10.1016/j.drudis.2021.01.031. Epub 2021 Feb 4.
Ionic liquids (ILs) are remarkable chemical compounds with applications in many areas of modern science. They are increasingly recognized as promising compounds to fight microorganisms in both planktonic and biofilm states, contributing to reinvent the antimicrobial pipeline. Biofilm-related infections are particularly challenging given that the scientific community has not yet identified a reliable control strategy. Understanding of the action of ILs in biofilm control is is still in a very early stage. However, given the highly tunable nature and exceptional properties of ILs, they are excellent candidates for biofilm control. Here, we review the major advances in, and challenges tothe use of ILs for effective biofilm control.
离子液体（ILs）是一类具有显著特性的化合物，在现代科学的许多领域都有应用。它们正逐渐被认为是对抗浮游态和生物膜态微生物的有前途的化合物，有助于重新设计抗菌药物的研发管线。由于科学界尚未确定可靠的控制策略，与生物膜相关的感染尤其具有挑战性。尽管如此，鉴于离子液体具有高度可调的性质和特殊的性质，它们是控制生物膜的优秀候选物。在这里，我们综述了离子液体在有效控制生物膜方面的主要进展和挑战。
