Coultas D B, Howard C A, Peake G T, Skipper B J, Samet J M
Department of Medicine, University of New Mexico Medical Center, Albuquerque.
Am Rev Respir Dis. 1988 Apr;137(4):810-4. doi: 10.1164/ajrccm/137.4.810.
In a population-based survey of respiratory disease in New Mexico Hispanics, we validated self-reports of cigarette use by 1,317 subjects against salivary cotinine level and end-tidal carbon monoxide concentration. For identifying likely deceivers about cigarette smoking among self-reported never smokers and former smokers, we used cutoff values of 20 ng/ml and 8 parts per million (ppm) for salivary cotinine and carbon monoxide, respectively. Among males and females, age-standardized prevalences of current smokers based upon questionnaire reports were 30.9 and 27.1%, respectively. After adjustment for cotinine alone, these percentages were 36.2 for males and 31.1 for females, and after adjustment for cotinine and carbon monoxide level, the corresponding percentages were 39.1 for males and 33.2 for females. We conclude that self-reports about smoking habits may lead to underestimation of the prevalence of current smokers and that questionnaire responses should be validated with biologic markers of tobacco smoke exposure.
在一项针对新墨西哥州西班牙裔人群的呼吸道疾病的基于人群的调查中,我们对照唾液可替宁水平和呼出气体一氧化碳浓度,验证了1317名受试者关于吸烟情况的自我报告。为了识别自我报告的从不吸烟者和曾经吸烟者中可能在吸烟问题上说谎的人,我们分别将唾液可替宁和一氧化碳的临界值设定为20纳克/毫升和百万分之八(ppm)。根据问卷调查结果,男性和女性当前吸烟者的年龄标准化患病率分别为30.9%和27.1%。仅根据可替宁进行调整后,男性的这一比例为36.2%,女性为31.1%;在根据可替宁和一氧化碳水平进行调整后,相应的比例男性为39.1%,女性为33.2%。我们得出结论,关于吸烟习惯的自我报告可能会导致对当前吸烟者患病率的低估,问卷调查的回答应该用烟草烟雾暴露的生物标志物进行验证。