Department of Urology, Hospital Universitario Fundación Santa Fe de Bogotá, Universidad de los Andes School of Medicine, Bogotá, Colombia.
Department of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Bogotá, Colombia.
Neurourol Urodyn. 2021 Mar;40(3):819-828. doi: 10.1002/nau.24624. Epub 2021 Feb 7.
To determine the prevalence of nocturia and associated risk factors in the Colombian population aged ≥18 years old.
This is a cross-sectional population-based study conducted in 1060 participants in Colombia. Nocturia was assessed with the Spanish version of the ICIQ-OAB, using the ICS terminology. Descriptive statistics were used to evaluate nocturia prevalence. Logistic regression analysis was carried out to determine the association of nocturia with predefined variables.
The prevalence of nocturia was 55.9% and it was more common in women than men (53.96% vs. 46.04%; p = .004). At least three episodes of nocturia were observed in 20.37% of the participants who had a severe alteration in their quality of life (p < .01). The bivariate model showed an association between nocturia and obesity (odds ratio [OR], 1.69; 90% confidence interval [CI]: 1.22-2.34), diabetes mellitus (OR, 2.99; 90% CI: 1.86-4.83), high blood pressure (OR, 2.04; 90% CI: 1.52-2.72), cardiovascular disease (OR, 1.75; 90% CI: 1.08 - 2.83), depression (OR, 1.89; 90% CI: 1.23-2.89), obstructive sleep apnea (OR, 1.70; 90% CI: 1.17 - 2.46), and childhood enuresis (OR, 1.45; 90% CI: 1.04-2.02). The multivariate model showed an association with obesity (OR, 2.0; 95% CI: 1.14 - 3.51) in women, as well as age ≥ 65 years (OR, 3.18; 95% CI: 1.26 - 8.02) and erectile dysfunction (OR, 3.44; 95% CI: 1.21 - 9.72) in men. Childhood enuresis was significantly associated with nocturia in both genders (OR, 1.61; 95% CI: 1.09 - 2.40 in women and OR, 1.66; 95% CI: 1.09-2.52 in men).
There is a significant prevalence of nocturia in our population and a clear association with impaired quality of life. We consider important to inquire about history of childhood enuresis to define the risk of presenting nocturia in adulthood. Nocturia was associated with multiple comorbidities. Obesity and erectile dysfunction play an important role as modifiable risk factor.
确定哥伦比亚≥18 岁人群中夜尿症的患病率及其相关危险因素。
这是一项在哥伦比亚 1060 名参与者中进行的横断面基于人群的研究。使用国际尿控协会-下尿路症状问卷（ICIQ-OAB）的西班牙语版本，采用国际尿控协会的术语评估夜尿症。使用描述性统计评估夜尿症的患病率。进行逻辑回归分析以确定夜尿症与预定义变量的关联。
夜尿症的患病率为 55.9%，女性比男性更为常见（53.96%比 46.04%；p=0.004）。在生活质量受到严重影响的参与者中（p<0.01），至少有 3 次夜尿的参与者比例为 20.37%。双变量模型显示，夜尿症与肥胖症（比值比[OR]，1.69；95%置信区间[CI]：1.22-2.34）、糖尿病（OR，2.99；95%CI：1.86-4.83）、高血压（OR，2.04；95%CI：1.52-2.72）、心血管疾病（OR，1.75；95%CI：1.08-2.83）、抑郁症（OR，1.89；95%CI：1.23-2.89）、阻塞性睡眠呼吸暂停（OR，1.70；95%CI：1.17-2.46）和儿童遗尿症（OR，1.45；95%CI：1.04-2.02）相关。多变量模型显示，女性肥胖症（OR，2.0；95%CI：1.14-3.51）、年龄≥65 岁（OR，3.18；95%CI：1.26-8.02）和勃起功能障碍（OR，3.44；95%CI：1.21-9.72）与夜尿症相关。儿童遗尿症在两性中均与夜尿症显著相关（女性 OR，1.61；95%CI：1.09-2.40；男性 OR，1.66；95%CI：1.09-2.52）。
我们的人群中夜尿症的患病率较高，且与生活质量明显下降有关。我们认为，询问儿童遗尿症病史以确定成年后出现夜尿症的风险很重要。夜尿症与多种合并症相关。肥胖症和勃起功能障碍是重要的可改变的危险因素。
