Nakashima Keigo, Misawa Takeyuki, Kumagai Yu, Kitamura Hiroaki, Fujioka Syuichi, Yanaga Katsuhiko
Department of Surgery, The Jikei University Kashiwa Hospital, 163-1 Kashiwashita Kashiwashi, Chiba, 277-8567, Japan.
Division of Digestive Surgery, The Jikei University School of Medicine, 3-19-18 Nishishinbashi Minatoku, Tokyo, 105-8471, Japan.
Ann Med Surg (Lond). 2021 Jan 19;62:373-376. doi: 10.1016/j.amsu.2021.01.021. eCollection 2021 Feb.
Liver metastasis of submandibular gland carcinoma is not uncommon, yet its optimal management is still unclear. We report a case of resection of liver metastasis from submandibular gland carcinoma five years after the primary operation.
The patient was a 76-year-old male who had undergone resection of primary adenoid cystic carcinoma of the submandibular gland in 2012. On follow-up computed tomography (CT) five years after the initial operation, a tumor was found incidentally in hepatic segment 6. Magnetic resonance imaging (MRI) confirmed the lesion's presence. Based on imaging findings and medical history, the lesion was suspected to be a liver metastasis of the previous submandibular gland carcinoma. The patient underwent hepatic posterior sectionectomy. His postoperative course was uneventful except for minor bile leakage that subsided without surgical intervention, and he was discharged on postoperative day 25. Postoperative pathological examinations of the hepatic tumor showed exactly the same features seen in the primary submandibular gland carcinoma, and the diagnosis as metastasis from this carcinoma was confirmed.
Liver resection may be a reasonable choice of treatment for liver metastasis of submandibular gland carcinoma. Further evidence from studies with larger patient populations must be accumulated to confirm this.
We report our experience with a case of liver metastasis from submandibular gland carcinoma, which was resected five years after the primary operation.
下颌下腺癌肝转移并不罕见,但其最佳治疗方案仍不明确。我们报告一例在初次手术后五年切除下颌下腺癌肝转移灶的病例。
患者为一名76岁男性,2012年接受了下颌下腺原发性腺样囊性癌切除术。初次手术后五年的随访计算机断层扫描(CT)偶然发现肝脏第6段有一个肿瘤。磁共振成像(MRI)证实了该病变的存在。根据影像学检查结果和病史,怀疑该病变为先前下颌下腺癌的肝转移。患者接受了肝右后叶切除术。除了少量胆汁漏,未经手术干预自行消退外,他的术后过程顺利,术后第25天出院。肝肿瘤的术后病理检查显示与原发性下颌下腺癌完全相同的特征,确诊为该癌转移。
肝切除可能是下颌下腺癌肝转移的一种合理治疗选择。必须积累更多来自更大患者群体研究的证据来证实这一点。
我们报告了一例下颌下腺癌肝转移的病例,该病例在初次手术后五年进行了切除。