妊娠并发症与良性家族性关节过度松弛
Complications of pregnancy and benign familial joint hyperlaxity.
作者信息
Thornton J G, Hill J, Bird H A
机构信息
Department of Obstetrics and Gynaecology, General Infirmary, Leeds.
出版信息
Ann Rheum Dis. 1988 Mar;47(3):228-31. doi: 10.1136/ard.47.3.228.
Abstract
A family is described in which four generations were affected by benign familial joint hyperlaxity and, in the two generations for which obstetric data were available, pregnancies were complicated by unexplained mid-trimester vaginal bleeding. This prompted a study to determine whether unexplained antepartum haemorrhage (APH) and premature rupture of the membranes (PROM) both of which might reflect the structure of fetal collagen, were associated with joint hyperlaxity in offspring. The joint hyperlaxity of children born from such pregnancies was slightly greater than that found in age matched children born from uncomplicated pregnancies.
摘要
本文描述了一个家族，其中四代人都患有良性家族性关节过度松弛症。在有产科数据的两代人中，孕期出现了不明原因的孕中期阴道出血。这促使开展一项研究，以确定不明原因的产前出血（APH）和胎膜早破（PROM）（这两者都可能反映胎儿胶原蛋白的结构）是否与后代的关节过度松弛有关。此类妊娠所生子女的关节过度松弛程度略高于同期出生的无并发症妊娠子女。
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