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移植用胰腺移植物的后台手术:对并发症的影响

Back-table surgery pancreas allograft for transplantation: Implications in complications.

作者信息

Briceño Javier, Sánchez-Hidalgo Juan Manuel, Arjona-Sanchez Alvaro

机构信息

Department of General and Digestive Surgery, Reina Sofia University Hospital, Cordoba 14004, Spain.

出版信息

World J Transplant. 2021 Jan 18;11(1):1-6. doi: 10.5500/wjt.v11.i1.1.

DOI:10.5500/wjt.v11.i1.1
PMID:33552938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7829682/
Abstract

To describe the main aspects of back-table surgery in pancreatic graft and the problems arising from poor technique. Back-table surgery for pancreatic graft is a complex, meticulous and laborious technique on which the success of implant surgery and perioperative results depends. The technique can be described in the following steps: Preparation of the sterile table, inspection of the pancreas-spleen block, management of the duodenum, identification of the bile duct, preparation of the portal vein, preparation of the own graft arteries and anastomosis to the arterial graft, spleen management and graft preservation prior to implantation in the recipient. A careful inspection of the pancreas-spleen block should be performed. It is important to identify the stump of the main bile duct, the portal vein cuff, and the arrangement of the superior mesenteric artery and splenic artery. The redundant duodenum must be removed. The availability of a good venous cuff facilitates the portal vein anastomosis and the positioning of the graft, two key points to prevent thrombosis. The section line of the arteries must be clean, without atherosclerosis, to prevent arterial thrombosis. The superior and splenic mesenteric arteries are generally separated by dense fibrolymphatic tissue. The artery can be reconstructed by interposing a "Y" graft from the donor iliac artery; or with an end-to-end anastomosis between the splenic artery and the superior mesenteric artery. An exquisite technique of bench work helps to prevent the most feared complications of pancreas transplantation: Thrombosis and graft pancreatitis.

摘要

描述胰腺移植后台手术的主要方面以及技术欠佳所引发的问题。胰腺移植后台手术是一项复杂、精细且费力的技术,植入手术的成功及围手术期结果均取决于此。该技术可按以下步骤描述:准备无菌手术台、检查胰脾块、处理十二指肠、识别胆管、准备门静脉、准备自体移植动脉并与动脉移植物吻合、处理脾脏以及在植入受者前保存移植物。应仔细检查胰脾块。识别胆总管残端、门静脉袖套以及肠系膜上动脉和脾动脉的排列非常重要。必须切除多余的十二指肠。良好的静脉袖套有助于门静脉吻合及移植物定位,这是预防血栓形成的两个关键点。动脉的切断线必须干净,无动脉粥样硬化,以防止动脉血栓形成。肠系膜上动脉和脾动脉通常被致密的纤维淋巴组织分隔。动脉可通过插入供体髂动脉的“Y”形移植物进行重建;或者脾动脉与肠系膜上动脉进行端端吻合。精湛的台上操作技术有助于预防胰腺移植最可怕的并发症:血栓形成和移植胰腺炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a714/7829682/4f75f28796ac/WJT-11-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a714/7829682/4f75f28796ac/WJT-11-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a714/7829682/4f75f28796ac/WJT-11-1-g001.jpg

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本文引用的文献

1
Machine Perfusion and the Pancreas: Will It Increase the Donor Pool?机器灌注与胰腺:它会增加供体池吗?
Curr Diab Rep. 2019 Jul 10;19(8):56. doi: 10.1007/s11892-019-1165-y.
2
Retroperitoneal Pancreas Transplantation With the Use of Duodenal Drainage via "Button Technique": First Clinical Practice (Case Report).采用“纽扣技术”十二指肠引流的腹膜后胰腺移植:首例临床实践(病例报告)
Transplant Proc. 2017 Dec;49(10):2347-2351. doi: 10.1016/j.transproceed.2017.10.005.
3
Surgery of pancreas transplantation.胰腺移植手术。
胰腺移植中肝总动脉重建的疗效及影响评估:一项随机对照试验
J Clin Med. 2022 Apr 18;11(8):2258. doi: 10.3390/jcm11082258.
Curr Opin Organ Transplant. 2017 Aug;22(4):389-397. doi: 10.1097/MOT.0000000000000434.
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Exocrine drainage in vascularized pancreas transplantation in the new millennium.新千年血管化胰腺移植中的外分泌引流
World J Transplant. 2016 Jun 24;6(2):255-71. doi: 10.5500/wjt.v6.i2.255.
5
Pancreas Transplantation in the Modern Era.现代胰腺移植
Gastroenterol Clin North Am. 2016 Mar;45(1):145-66. doi: 10.1016/j.gtc.2015.10.008. Epub 2016 Jan 13.
6
[Pancreas transplantation and venous thrombosis: multivariate analysis of risk factors].[胰腺移植与静脉血栓形成:危险因素的多变量分析]
Prog Urol. 2012 Jun;22(7):402-7. doi: 10.1016/j.purol.2012.01.016. Epub 2012 Mar 3.
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Clin Transplant. 2011 Mar-Apr;25(2):E103-12. doi: 10.1111/j.1399-0012.2011.01414.x. Epub 2011 Mar 1.
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Surgical techniques for pancreas transplantation.胰腺移植的外科技术。
Curr Opin Organ Transplant. 2010 Feb;15(1):102-11. doi: 10.1097/MOT.0b013e32833553de.
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Revascularization of the gastroepiploic artery in pancreas transplant.胰肾联合移植术中胃网膜动脉血运重建术
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