Chittajallu Vibhu, Simons-Linares Carlos Roberto, Oshilaja Olaronke, Chahal Prabhleen
Department of Internal Medicine, Cleveland Clinic, Cleveland, OH.
Digestive Disease and Surgery Institute, Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH.
ACG Case Rep J. 2021 Feb 3;8(2):e00513. doi: 10.14309/crj.0000000000000513. eCollection 2021 Feb.
Less than 4% of melanomas are of mucosal origin, with primary anorectal mucosal melanomas comprising a small subset. Mucosal melanomas are often diagnosed at an advanced stage due to delay in patient presentation and obscured tumor origins leading to a more aggressive behavior and less favorable prognosis when compared with cutaneous melanomas. We present a case of metastatic anorectal mucosal melanoma with a negative colonoscopy 1 year earlier.
不到4%的黑色素瘤起源于黏膜,原发性肛门直肠黏膜黑色素瘤仅占其中一小部分。由于患者就诊延迟以及肿瘤起源难以明确,黏膜黑色素瘤往往在晚期才被诊断出来,与皮肤黑色素瘤相比,其行为更具侵袭性,预后也更差。我们报告一例转移性肛门直肠黏膜黑色素瘤病例,该患者一年前结肠镜检查结果为阴性。