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手术及剂量递增放疗治疗一例桥小脑角颅内鳞状细胞癌

Surgery and dose-escalated radiotherapy for a intracranial squamous cell carcinoma of the cerebellopontine angle.

作者信息

Mula-Hussain Layth, Malone Julia, Dos Santos Marlise P, Alkherayf Fahad, Sinclair John, Malone Shawn

机构信息

Radiation Oncology Division, The Ottawa Hospital - University of Ottawa, Ottawa, ON, Canada.

Department of Medical Imaging, The Ottawa Hospital - University of Ottawa, and Ottawa Hospital Research Institute, Ottawa, ON, Canada.

出版信息

Clin Transl Radiat Oncol. 2021 Jan 27;27:99-102. doi: 10.1016/j.ctro.2021.01.010. eCollection 2021 Mar.

DOI:10.1016/j.ctro.2021.01.010
PMID:33553696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7851331/
Abstract

We report an extremely rare case of intracranial squamous cell carcinoma of the cerebellopontine angle. The patient underwent craniotomy for debulking of the lesion to relieve mass effect on the brainstem and to establish a tissue diagnosis. Cancer staging revealed no other primary cancers and no evidence of metastatic disease. Postoperatively, he received image-guided intensity-modulated radiotherapy to the tumor bed followed by fractionated radiosurgery boost to the gross residual disease for a total average dose of 7000 cGy. He had a complete response to radiation and remains 42-months' disease-free post-treatment.

摘要

我们报告了一例极其罕见的桥小脑角颅内鳞状细胞癌病例。患者接受了开颅手术以切除病变组织,减轻对脑干的占位效应并进行组织诊断。癌症分期显示无其他原发性癌症且无转移疾病证据。术后,他接受了针对肿瘤床的图像引导调强放疗,随后对大体残留病灶进行分次立体定向放射外科增敏,总平均剂量为7000厘戈瑞。他对放疗有完全反应,治疗后已无病生存42个月。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3de/7851331/434bab38ff17/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3de/7851331/1837dfcfe84c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3de/7851331/4661561557f6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3de/7851331/434bab38ff17/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3de/7851331/1837dfcfe84c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3de/7851331/4661561557f6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3de/7851331/434bab38ff17/gr3.jpg

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本文引用的文献

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Intracranial Squamous Cell Carcinoma Arising From a Cerebellopontine Angle Epidermoid Cyst Remnant Four Decades After Partial Resection.部分切除术后四十年,起源于桥小脑角表皮样囊肿残余的颅内鳞状细胞癌
Front Oncol. 2019 Jul 30;9:694. doi: 10.3389/fonc.2019.00694. eCollection 2019.
2
Treatment and Survival Outcomes of Primary Intracranial Squamous Cell Carcinoma.原发性颅内鳞状细胞癌的治疗和生存结果。
World Neurosurg. 2019 May;125:e1-e9. doi: 10.1016/j.wneu.2018.11.252. Epub 2018 Dec 18.
3
Primary Intracranial Squamous Cell Carcinoma Arising De Novo: A Case Report and Review of the Literature.
原发性颅内原发性鳞状细胞癌:一例报告并文献复习
World Neurosurg. 2018 Dec;120:372-381. doi: 10.1016/j.wneu.2018.08.067. Epub 2018 Aug 23.
4
Intracranial squamous cell carcinoma arising in a cerebellopontine angle epidermoid cyst: A case report and literature review.起源于桥小脑角表皮样囊肿的颅内鳞状细胞癌:一例报告及文献复习
Medicine (Baltimore). 2017 Dec;96(51):e9423. doi: 10.1097/MD.0000000000009423.
5
Image-guided, intensity-modulated radiation therapy (IG-IMRT) for skull base chordoma and chondrosarcoma: preliminary outcomes.图像引导下的调强放射治疗(IG-IMRT)用于颅底脊索瘤和软骨肉瘤:初步结果。
Neuro Oncol. 2015 Jun;17(6):889-94. doi: 10.1093/neuonc/nou347. Epub 2014 Dec 27.
6
An analysis of intracranial epidermoid tumors with malignant transformation: treatment and outcomes.颅内表皮样囊肿恶变的分析:治疗与结果
Clin Neurol Neurosurg. 2013 Jul;115(7):1071-8. doi: 10.1016/j.clineuro.2012.10.026. Epub 2012 Dec 6.
7
Primary intracranial basaloid squamous cell carcinoma: an enigma.原发性颅内基底样鳞状细胞癌:一个谜。
Neurol Neurochir Pol. 2012 Sep-Oct;46(5):489-95. doi: 10.5114/ninp.2012.31361.
8
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Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S36-41. doi: 10.1016/j.ijrobp.2009.08.078.
9
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J Neurooncol. 2005 Sep;74(2):187-94. doi: 10.1007/s11060-004-5175-4.
10
Imaging findings associated with childhood primary intracranial squamous cell carcinoma.与儿童原发性颅内鳞状细胞癌相关的影像学表现。
AJNR Am J Neuroradiol. 2003 Jan;24(1):109-11.