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经口圆形吻合器吻合术治疗上消化道恶性肿瘤切除术后结局分析。

Analysis of outcomes of a transoral circular stapled anastomosis following major upper gastrointestinal cancer resection.

机构信息

Department of Surgery, Guy's and St Thomas' NHS Foundation Trust, London, UK.

King's College London, UK.

出版信息

Dis Esophagus. 2021 Nov 11;34(11). doi: 10.1093/dote/doab004.

Abstract

BACKGROUND

Esophageal anastomoses performed following esophagectomy and total gastrectomy are technically challenging with a significant risk of anastomotic leak. A safe, reliable, and easy anastomotic technique is required to improve patient outcomes and reduce morbidity.

METHOD

This paper analyses 328 consecutive patients who underwent transoral circular stapled esophageal anastomosis (ORVIL™) from a prospectively collected single-center database between December 2011 and February 2019.

RESULTS

Two hundred and twenty-seven esophagectomies and 101 gastrectomies were performed using OrVil™ anastomoses. The mean patient age was 63.7 years. Of 328 consecutive OrVil™-based anastomoses, there were 10 clinically significant anastomotic leaks requiring radiological or operative intervention (3.05%). Twenty-eight (8.54%) patients developed anastomotic stricture, all of which were successfully treated with endoscopic balloon dilatation (a median of 1 dilatation was required per patient).

CONCLUSION

The OrVil™ anastomotic technique is reliable and safe to perform. This is the largest reported series of the OrVil™ anastomotic technique to date. Leak rates and anastomotic dilations were similar to other reported series. Based on our experience, we consider the use of the OrVil™ device for reconstruction after major upper GI resection to be safe and reliable.

摘要

背景

食管切除术和全胃切除术后的食管吻合具有技术挑战性,吻合口漏的风险很大。需要一种安全、可靠且易于操作的吻合技术,以改善患者的预后并降低发病率。

方法

本文分析了 2011 年 12 月至 2019 年 2 月期间,从一个前瞻性收集的单中心数据库中连续 328 例接受经口圆形吻合器食管吻合术(ORVIL™)的患者。

结果

227 例食管切除术和 101 例胃切除术采用 OrVil™吻合术。患者平均年龄为 63.7 岁。在连续 328 例基于 OrVil™的吻合中,有 10 例临床显著吻合口漏需要放射或手术干预(3.05%)。28 例(8.54%)患者发生吻合口狭窄,所有患者均通过内镜球囊扩张成功治疗(每位患者平均需要 1 次扩张)。

结论

OrVil™吻合技术可靠且安全。这是迄今为止报道的最大规模的 OrVil™吻合技术系列。漏率和吻合口扩张与其他报道的系列相似。根据我们的经验,我们认为在主要上消化道切除术后使用 OrVil™装置进行重建是安全可靠的。

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