Florida Medical Entomology Laboratory, University of Florida, Vero Beach, FL, USA.
Department of Biological Sciences, University of Southern Mississippi, Hattiesburg, MS, USA.
J Med Entomol. 2021 May 15;58(3):1405-1411. doi: 10.1093/jme/tjaa286.
Recurrence of local transmission of Zika virus in Puerto Rico is a major public health risk to the United States, where mosquitoes Aedes aegypti (Linnaeus) and Aedes mediovittatus (Coquillett) are abundant. To determine the extent to which Ae. mediovittatus are capable of transmitting Zika virus and the influence of viremia, we evaluated infection and transmission in Ae. mediovittatus and Ae. aegypti from Puerto Rico using serial dilutions of infectious blood. Higher doses of infectious blood resulted in greater infection rates in both mosquitoes. Aedes aegypti females were up to twice as susceptible to infection than Ae. mediovittatus, indicating a more effective midgut infection barrier in the latter mosquito species. Aedes aegypti exhibited higher disseminated infection (40-95%) than Ae. mediovittatus (<5%), suggesting a substantial midgut escape barrier in Ae. mediovittatus. For Ae. aegypti, transmission rates were low over a range of doses of Zika virus ingested, suggesting substantial salivary gland barriers.
波多黎各的寨卡病毒局部传播再次出现，这对美国构成了重大公共卫生风险，因为美国蚊子埃及伊蚊（Linnaeus）和mediovittatus 属埃及伊蚊（Coquillett）大量存在。为了确定 mediovittatus 属埃及伊蚊传播寨卡病毒的程度以及病毒血症的影响，我们使用传染性血液的系列稀释液评估了来自波多黎各的 mediovittatus 属埃及伊蚊和埃及伊蚊的感染和传播情况。较高剂量的传染性血液会导致两种蚊子的感染率更高。埃及伊蚊雌性比 mediovittatus 属埃及伊蚊更容易感染，表明后者的中肠感染屏障更有效。埃及伊蚊表现出更高的（40-95%）播散感染，而 mediovittatus 属埃及伊蚊则较低（<5%），表明 mediovittatus 属埃及伊蚊中肠有大量逃逸屏障。对于埃及伊蚊，在摄入不同剂量寨卡病毒的范围内，传播率较低，表明唾液腺有大量屏障。
