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阻塞性睡眠呼吸暂停合并心房颤动患者的心率测量:评估苹果手表与遥测数据一致性的前瞻性初步研究

Heart Rate Measurements in Patients with Obstructive Sleep Apnea and Atrial Fibrillation: Prospective Pilot Study Assessing Apple Watch's Agreement With Telemetry Data.

作者信息

Huynh Pauline, Shan Rongzi, Osuji Ngozi, Ding Jie, Isakadze Nino, Marvel Francoise A, Sharma Garima, Martin Seth S

机构信息

School of Medicine, Johns Hopkins University, Baltimore, MD, United States.

Ciccarone Center for the Prevention of Cardiovascular Disease, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

出版信息

JMIR Cardio. 2021 Feb 8;5(1):e18050. doi: 10.2196/18050.

Abstract

BACKGROUND

Patients with obstructive sleep apnea (OSA) are at a higher risk for atrial fibrillation (AF). Consumer wearable heart rate (HR) sensors may be a means for passive HR monitoring in patients with AF.

OBJECTIVE

The aim of this study was to assess the Apple Watch's agreement with telemetry in measuring HR in patients with OSA in AF.

METHODS

Patients with OSA in AF were prospectively recruited prior to cardioversion/ablation procedures. HR was sampled every 10 seconds for 60 seconds using telemetry and an Apple Watch concomitantly. Agreement of Apple Watch with telemetry, which is the current gold-standard device for measuring HR, was assessed using mixed effects limits agreement and Lin's concordance correlation coefficient.

RESULTS

A total of 20 patients (mean 66 [SD 6.5] years, 85% [n=17] male) participated in this study, yielding 134 HR observations per device. Modified Bland-Altman plot revealed that the variability of the paired difference of the Apple Watch compared with telemetry increased as the magnitude of HR measurements increased. The Apple Watch produced regression-based 95% limits of agreement of 27.8 - 0.3 × average HR - 15.0 to 27.8 - 0.3 × average HR + 15.0 beats per minute (bpm) with a mean bias of 27.8 - 0.33 × average HR bpm. Lin's concordance correlation coefficient was 0.88 (95% CI 0.85-0.91), suggesting acceptable agreement between the Apple Watch and telemetry.

CONCLUSIONS

In patients with OSA in AF, the Apple Watch provided acceptable agreement with HR measurements by telemetry. Further studies with larger sample populations and wider range of HR are needed to confirm these findings.

摘要

背景

阻塞性睡眠呼吸暂停(OSA)患者发生心房颤动(AF)的风险更高。消费级可穿戴心率(HR)传感器可能是对AF患者进行被动HR监测的一种手段。

目的

本研究旨在评估Apple Watch在测量AF合并OSA患者心率方面与遥测技术的一致性。

方法

在进行心脏复律/消融手术前,前瞻性招募AF合并OSA患者。使用遥测技术和Apple Watch同时每隔10秒采集一次HR,共采集60秒。使用混合效应一致性界限和Lin一致性相关系数评估Apple Watch与作为当前测量HR金标准设备的遥测技术之间的一致性。

结果

共有20例患者(平均年龄66 [标准差6.5]岁,85% [n = 17]为男性)参与本研究,每个设备获得134次HR观测值。改良的布兰德-奥特曼图显示,与遥测技术相比,Apple Watch配对差值的变异性随着HR测量值的增大而增加。Apple Watch基于回归的95%一致性界限为每分钟27.8 - 0.3×平均HR - 15.0至27.8 - 0.3×平均HR + 15.0次心跳(bpm),平均偏差为27.8 - 0.33×平均HR bpm。Lin一致性相关系数为0.88(95%可信区间0.85 - 0.91),表明Apple Watch与遥测技术之间具有可接受的一致性。

结论

在AF合并OSA患者中,Apple Watch在HR测量方面与遥测技术具有可接受的一致性。需要进一步开展更大样本量和更广泛HR范围的研究来证实这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aac/8411424/1ba5631d5035/cardio_v5i1e18050_fig1.jpg

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