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医源性干眼疾病:应对白内障术后不适的难题。一篇P.I.C.A.S.S.O.委员会叙述性综述。

Iatrogenic Dry Eye Disease: Dealing with the Conundrum of Post-Cataract Discomfort. A P.I.C.A.S.S.O. Board Narrative Review.

作者信息

Mencucci Rita, Vignapiano Roberto, Rubino Pierangela, Favuzza Eleonora, Cantera Emilia, Aragona Pasquale, Rolando Maurizio

机构信息

Eye Clinic, NEUROFARBA Department, University of Florence, Florence, Italy.

Ophthalmology, University of Parma, Parma, Italy.

出版信息

Ophthalmol Ther. 2021 Jun;10(2):211-223. doi: 10.1007/s40123-021-00332-7. Epub 2021 Feb 8.

DOI:10.1007/s40123-021-00332-7
PMID:33555571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8079532/
Abstract

The incidence and prevalence of dry eye disease (DED) after cataract surgery is greatly underestimated. The severity of dry eye symptoms has been reported to peak 7 days after cataract surgery and may persist for months, significantly affecting patients' quality of life (QoL). The importance of considering surgical outcomes not only in terms of visual acuity, but also in terms of the patients' QoL, necessitates the assessment and evaluation of the ocular surface by the cataract surgeon prior to the procedure. This narrative review, drafted by the P.I.C.A.S.S.O. (Italian Partners for the Correction of Ocular Surface Alterations) board, analyses the physiopathology of post-cataract surgery DED and highlights the pre-, intra- and postoperative risk factors that may alter ocular surface homeostasis; it proposes a practical comprehensive algorithm for the prevention, treatment and management of DED associated with cataract surgery. Particular attention needs to be paid to the pre- and intraoperative risk factors to reduce the incidence of postoperative dry eye and to improve cataract surgery outcome.

摘要

白内障手术后干眼症(DED)的发病率和患病率被严重低估。据报道,干眼症状的严重程度在白内障手术后7天达到峰值,并可能持续数月,严重影响患者的生活质量(QoL)。不仅要从视力方面,还要从患者的生活质量方面考虑手术结果,这就要求白内障手术医生在手术前对眼表进行评估和评价。本叙述性综述由P.I.C.A.S.S.O.(意大利眼表改变矫正合作伙伴)委员会起草,分析了白内障手术后干眼症的病理生理学,并强调了可能改变眼表稳态的术前、术中和术后危险因素;它提出了一种实用的综合算法,用于预防、治疗和管理与白内障手术相关的干眼症。需要特别关注术前和术中的危险因素,以降低术后干眼症的发生率,并改善白内障手术的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44a1/8079532/f598937c1a5a/40123_2021_332_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44a1/8079532/0906a06e489d/40123_2021_332_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44a1/8079532/c1a863e08752/40123_2021_332_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44a1/8079532/f598937c1a5a/40123_2021_332_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44a1/8079532/0906a06e489d/40123_2021_332_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44a1/8079532/c1a863e08752/40123_2021_332_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44a1/8079532/f598937c1a5a/40123_2021_332_Fig3_HTML.jpg

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Modern approach to the treatment of dry eye, a complex multifactorial disease: a P.I.C.A.S.S.O. board review.现代治疗干眼病的方法:一种复杂的多因素疾病:P.I.C.A.S.S.O. 董事会综述。
Br J Ophthalmol. 2021 Apr;105(4):446-453. doi: 10.1136/bjophthalmol-2019-315747. Epub 2020 Jul 23.
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