Mencucci Rita, Stefanini Simone, Favuzza Eleonora, Cennamo Michela, De Vitto Chiara, Mossello Enrico
Eye Clinic, Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.
Division of Geriatric and Intensive Care Medicine, Azienda Ospedaliero Universitaria Careggi, and Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Front Med (Lausanne). 2023 Mar 16;10:1110383. doi: 10.3389/fmed.2023.1110383. eCollection 2023.
Cataract is a leading cause of visual impairment in old age. Lens opacification is notoriously associated with several geriatric conditions, including frailty, fall risk, depression and cognitive impairment. The association is largely attributable to visual impairment, while other mechanisms, associated with extraocular comorbidity and lifestyle, might partly explain this correlation. Available literature suggests that cataract surgery may be effective in decreasing fall risk, improving depressive symptoms and limiting the risk of cognitive impairment and dementia incidence, although intervention studies on these outcomes are still limited. In this review we also emphasize the need to move from the concept of visual acuity to functional vision, especially in the context of the geriatric patient. Research is needed regarding the effect on the cited outcomes of different cataract treatment strategies, such as systematic bilateral versus monolateral surgery and use of different intraocular lenses.
白内障是老年人视力损害的主要原因。晶状体混浊与多种老年疾病密切相关,包括身体虚弱、跌倒风险、抑郁和认知障碍。这种关联在很大程度上归因于视力损害,而与眼外合并症和生活方式相关的其他机制可能部分解释了这种相关性。现有文献表明,白内障手术可能有效降低跌倒风险、改善抑郁症状并限制认知障碍和痴呆症发病率的风险,尽管关于这些结果的干预研究仍然有限。在本综述中,我们还强调需要从视力概念转向功能性视力,尤其是在老年患者的背景下。需要研究不同白内障治疗策略对上述结果的影响,例如系统性双侧手术与单侧手术以及不同人工晶状体的使用。