Kwai Chung Hospital, Hong Kong, China.
Private Practice, Hong Kong, China.
CNS Neurosci Ther. 2021 Mar;27 Suppl 1(Suppl 1):12-19. doi: 10.1111/cns.13375.
Recent research on second-generation long-acting injectable antipsychotics (LAI SGAs) has proven its effectiveness in minimizing medication nonadherence problem and reducing relapses. Administered by medical professionals, making quick detection of nonadherence possible, long-acting injectable antipsychotics (LAIs) facilitate immediate intervention and recovery process, and thus are favored by psychiatrists. Despite a higher initial cost with LAIs, the subsequent schizophrenia-related health costs for hospitalizations and outpatients are greatly reduced. With reference to guidelines published by psychiatric associations around the globe, this article looks at scenarios in Hong Kong on the management of severe mentally ill patients with regard to the use of a host of psychosocial interventions as well as LAI SGAs as a preferable treatment. In particular, it examines the benefits of using LAI SGAs for Hong Kong patients who demonstrated high nonadherence treatment rates due to their social environment. It assesses the rationale behind the early usages of LAI SGAs, which help to provide better recovery outcomes for patients.
最近对第二代长效抗精神病药(LAI SGAs)的研究证明,它在最大限度地减少药物不依从问题和减少复发方面非常有效。由医疗专业人员管理,可快速检测不依从,长效注射抗精神病药(LAIs)有助于立即进行干预和康复过程,因此深受精神科医生的青睐。尽管 LAI 的初始成本较高,但随后与精神分裂症相关的住院和门诊医疗费用会大大降低。本文参考全球精神病学协会发布的指南,研究了香港严重精神病患者管理中使用各种心理社会干预措施以及 LAI SGAs 作为首选治疗方法的情况。特别是,它研究了 LAI SGAs 对香港患者的益处,因为他们的社会环境导致治疗依从性高。它评估了早期使用 LAI SGAs 的基本原理,这有助于为患者提供更好的康复结果。