Neonatal Research Unit, Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.
Research Unit Interdisciplinary Developmental Neuroscience, Dept. Phoniatrics, Medical University of Graz, Austria.
Early Hum Dev. 2021 Mar;154:105304. doi: 10.1016/j.earlhumdev.2020.105304. Epub 2020 Dec 26.
Identifying altered motor development at an early stage is crucial for infants born extremely preterm (EPT), as they face a high risk of long-term neurodevelopmental impairment. The Prechtl General Movement Assessment (GMA), including the Motor Optimality Score Revised (MOS-R), can provide important insights into these infants' later neurodevelopmental function.
To compare age-specific movements and postures in infants born EPT compared to term-born controls at three months corrected age.
A retrospective observational study design.
53 infants born EPT (mean gestational age 25 weeks; 23-26) were included and matched for gender and recording age with 53 term-born controls (mean gestational age 40 weeks, 37-41).
GMA including the MOS-R at three months corrected age (re-analysis of video-recordings).
Of the infants born EPT, 19% showed aberrant fidgety movements (FMs); all term-born infants had normal FMs. There was a significant difference in MOS-R (p≤0.001) between controls (median = 26, IQR 26-28) and EPT infants (median = 18, IQR 17-21), as well as in all subcategories of the MOS-R. The EPT group had a significantly higher number of infants showing atypical movement and postural patterns as well as a reduced repertoire for the age compared to the controls. All infants born EPT moved monotonously and jerky. P-values were all <0.001.
Infants born EPT have an altered early motor development. The MOS-R may contribute to further understanding of motor performance in this group of children since it can detect neurological- and motor alterations at a very early age.
对于极早产儿（EPT）来说，早期识别运动发育异常至关重要，因为他们面临着长期神经发育障碍的高风险。Prechtl 一般性运动评估（GMA），包括运动优化评分修订版（MOS-R），可以为这些婴儿的后期神经发育功能提供重要的见解。
比较出生时极早产儿（EPT）与足月出生对照组婴儿在矫正 3 个月龄时的特定年龄运动和姿势。
回顾性观察性研究设计。
纳入 53 名 EPT 出生婴儿（平均胎龄 25 周；23-26），并按性别和记录年龄与 53 名足月出生对照组婴儿（平均胎龄 40 周；37-41）相匹配。
包括矫正 3 个月龄时的 GMA 和 MOS-R（视频记录的重新分析）。
在 EPT 出生的婴儿中，19%出现异常烦躁运动（FM）；所有足月出生的婴儿均有正常 FM。对照组（中位数=26，IQR 26-28）和 EPT 婴儿（中位数=18，IQR 17-21）之间的 MOS-R 存在显著差异（p≤0.001），以及 MOS-R 的所有亚类。与对照组相比，EPT 组显示出更多婴儿具有非典型运动和姿势模式，并且年龄的运动模式范围缩小。所有 EPT 出生的婴儿运动单调且急促。所有 P 值均<0.001。
EPT 出生的婴儿运动发育异常。MOS-R 可能有助于进一步了解这组儿童的运动表现，因为它可以在非常早期检测到神经和运动异常。
